Continuous Positive Airway Pressure and Cardiovascular Events in Patients with Obstructive Sleep Apnea

被引：0
作者：
Athanasia Pataka
Renata L. Riha
机构：
[1] University of Thessaloniki,Department of Respiratory Medicine, Respiratory Failure Unit, G. Papanikolaou Hospital
[2] Royal Infirmary of Edinburgh,Department of Sleep Medicine
来源：
Current Cardiology Reports | 2013年 / 15卷
关键词：
Continuous positive airway pressure; CPAP; Obstructive sleep apnea; Heart failure; Cardiovascular disease; Cerebrovascular disease; Review;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The obstructive sleep apnea syndrome (OSAS) is associated with the development/worsening of cardiovascular disease. OSAS is considered to be an independent risk factor for hypertension and is linked to increased mortality in the context of coronary heart disease, the development of cardiac arrhythmias and increased risk of developing mild pulmonary hypertension. OSAS is also associated with cerebrovascular mortality and morbidity. In heart failure, OSAS can lead to worsening of symptoms. Treatment of OSAS using positive airways pressure therapy (PAP) has been shown in randomized, controlled trials in selected populations to reduce some, but not all of these cardiovascular and cerebrovascular risks. Unequivocal evidence of causality for OSAS in the development, progression, and outcomes of these disorders in all individuals suffering from them, is lacking. Good quality long-term morbidity and mortality data for the effects of OSAS on cardiometabolic health and the impact of PAP treatment are likewise limited.
引用
收藏
相关论文
共 399 条
  • [1] Marin JM(2005)Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnea with or without treatment with continuous positive airway pressure: an observational study Lancet 365 1046-1053
  • [2] Carrizo SJ(2006)Continuous positive airways pressure for obstructive sleep apnea in adults Cochrane Database Syst Rev 3 907-914
  • [3] Vicente E(2009)Epidemiology of sleep apnea/hypoapnea syndrome and sleep-disordered breathing Eur Respir J 33 1400-1405
  • [4] Agusti AG(2003)The relationship between congestive heart failure, sleep apnea, and mortality in older men Chest 124 308-313
  • [5] Giles TL(2000)Snoring and risk of cardiovascular disease in women J Am Coll Cardiol 35 1829-1836
  • [6] Lasserson TJ(2000)Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study: Sleep Heart Health Study JAMA 283 1378-1384
  • [7] Smith BJ(2000)Prospective study of the association between sleep-disordered breathing and hypertension N Engl J Med 342 19-25
  • [8] White J(2001)Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study Am J Respir Crit Care Med 163 735-741
  • [9] Wright J(2004)Obstructive sleep apnea is independently associated with an increased prevalence of metabolic syndrome Eur Heart J 25 156-178
  • [10] Cates CJ(2007)Sleep apnea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms, and research priorities. Management Committee of EU COST ACTION B26 Eur Respir J 29 364-367
12345678910