Reaction of 4-Hydroxyacridin-9(10H)-one and 4-Hydroxyacridine-9(10H)-thione with α,ω-Alkyl DibromidesReaktion von 4-Hydroxyacridin-9(10H)-on und 4-Hydroxyacridin-9(10H)-thion mit α,ω-Alkyldibromiden

被引：0

作者：

Jean-Pierre Galy

Anne-Marie Galy

Alain Vichet

José Elguero

机构：

[1] URA-CNRS 1411,

[2] Faculté des Sciences et Techniques de Saint-Jéôme,undefined

[3] F-13397 Marseille Cédex 20,undefined

[4] France,undefined

[5] Instituto de Química Médica,undefined

[6] CSIC,undefined

[7] E-28006 Madrid,undefined

[8] Spain,undefined

来源：

Monatshefte für Chemie / Chemical Monthly | 1998年 / 129卷

关键词：

Keywords. 4-Hydroxyacridinone; 4-Hydroxyacridine thione; 4-Methoxyacridinone; 4-Methoxyacridine thione; Alkylation.;

D O I：

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学科分类号：

摘要：

Starting from 4-hydroxyacridin-9(10H)-one (1) and 4-hydroxyacridine-9(10H)-thione (2), a series of bis-derivatives was prepared, among them the bridged bis-acridin-(10H)-ones 9–14 and the bis-mercapto-(9H)-acridines 15–18. The reactivity of the 2- and 4-hydroxy series was compared; it was found that it is harder to demethylate 4-methoxy derivatives than their 2-methoxy analogues.

引用

页码：1199 / 1205

页数：6