Germline BAP1 mutations predispose to malignant mesothelioma

被引：0
作者：
Joseph R Testa
Mitchell Cheung
Jianming Pei
Jennifer E Below
Yinfei Tan
Eleonora Sementino
Nancy J Cox
A Umran Dogan
Harvey I Pass
Sandra Trusa
Mary Hesdorffer
Masaki Nasu
Amy Powers
Zeyana Rivera
Sabahattin Comertpay
Mika Tanji
Giovanni Gaudino
Haining Yang
Michele Carbone
机构：
[1] Cancer Biology Program,Department of Medicine
[2] Fox Chase Cancer Center,Department of Human Genetics
[3] University of Chicago,Earth Sciences Department
[4] University of Chicago,Department of Chemical and Biochemical Engineering
[5] King Fahd University of Petroleum and Minerals,Department of Molecular Biosciences and Bioengineering
[6] University of Iowa,Department of Pathology
[7] New York University,undefined
[8] Langone Medical Center and Cancer Center,undefined
[9] Mesothelioma Applied Research Foundation,undefined
[10] University of Hawaii Cancer Center,undefined
[11] University of Hawaii at Manoa,undefined
[12] University of Hawaii at Manoa,undefined
[13] John A. Burns School of Medicine,undefined
[14] University of Hawaii at Manoa,undefined
来源：
Nature Genetics | 2011年 / 43卷
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摘要：
Joseph Testa, Michele Carbone and colleagues report that germline mutations in BAP1 predispose to malignant mesothelioma and uveal melanoma. They further hypothesize that mesothelioma predominates in BAP1 mutation carriers following exposure to asbestos.
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页码：1022 / 1025
页数：3
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