Four-year experience with methotrexate exposures.

被引：16

作者：

LoVecchio F. ^{[1
]}

Katz K. ^{[1
]}

Watts D. ^{[1
]}

Wood I. ^{[1
]}

机构：

[1] Banner Good Samaritan Regional Poison Center, Maricopa Medical Center, Department of Emergency Medicine, Phoenix, AZ

来源：

Journal of Medical Toxicology | 2008年 / 4卷 / 3期

关键词：

methotrexate; poisoning; toxicity; oral;

D O I：

10.1007/BF03161192

中图分类号：

学科分类号：

摘要：

INTRODUCTION: Unintentional methotrexate (MTX) acute oral overdose is rarely reported. METHODS: We conducted a retrospective chart review of all human exposure calls (>150,000 charts) for MTX ingestions reported to our Poison Center during 2000-2003. RESULTS: Thirteen patients met the criteria. The average amount of MTX ingested was 13.03 mg (data from 7 cases), and the average patient age was 43 years (20 months to 80 years). No significant toxicities occurred. DISCUSSION: Although intravenous MTX toxicity can be severe, this does not appear to be a phenomenon associated with either acute unintentional or suicidal oral ingestion.

引用

页码：149 / 150

页数：1

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