The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients

被引:0
作者
Ingrid Lunde
Sara Bremer
Karsten Midtvedt
Beata Mohebi
Miriam Dahl
Stein Bergan
Anders Åsberg
Hege Christensen
机构
[1] University of Oslo,Department of Pharmaceutical Biosciences, School of Pharmacy
[2] Oslo University Hospital,Department of Medical Biochemistry
[3] Rikshospitalet,Department of Transplant Medicine
[4] Oslo University Hospital,Department of Pharmacology
[5] Rikshospitalet,undefined
[6] Oslo University Hospital,undefined
[7] Rikshospitalet,undefined
来源
European Journal of Clinical Pharmacology | 2014年 / 70卷
关键词
Calcineurin inhibitors; Pharmacokinetics; Kidney recipients;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:685 / 693
页数:8
相关论文
共 251 条
[1]  
Staatz CE(2004)Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation Clin Pharmacokinet 43 623-653
[2]  
Tett SE(1995)Clinical pharmacokinetics of tacrolimus Clin Pharmacokinet 29 404-430
[3]  
Venkataramanan R(2007)CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients Clin Pharmacol Ther 82 711-725
[4]  
Swaminathan A(2001)The genetic determinants of the CYP3A5 polymorphism Pharmacogenetics 11 773-779
[5]  
Prasad T(2001)Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression Nat Genet 27 383-391
[6]  
Jain A(2005)CYP3A5 genetic polymorphisms in different ethnic populations Drug Metab Dispos 33 884-887
[7]  
Zuckerman S(2013)Impact of CYP3A5 genotype on tacrolimus versus midazolam clearance in renal transplant recipients: new insights in CYP3A5-mediated drug metabolism Pharmacogenomics 14 1467-1480
[8]  
Warty V(2009)A population pharmacokinetic model of ciclosporin applicable for assisting dose management of kidney transplant recipients Clin Pharmacokinet 48 615-623
[9]  
McMichael J(2013)Personalized tacrolimus doses determined by CYP3A5 genotype for induction and maintenance phases of kidney transplantation Clin Ther 35 1762-1769
[10]  
Lever J(2013)Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation Transpl Int 95 821-827