Abstract—: The article considers the development of a national system for monitoring emissions of climatically active substances. It is shown that the climate agenda is becoming increasingly interwoven with economic issues, and in this regard must be part of any long-term strategy for national socio-economic development. The development of the Critical Innovation Project of National Significance (Critical Project) on Climate in Russia aims to integrate natural science knowledge for the purposes of more effective economic management. The general structure of the project and interactions between individual consortiums are considered. The objectives of economic calculations involved in the project are formulated. It is concluded that the development of a monitoring system of emissions of climatically active substances for primary use as support for applied solutions in the field of economic policy involves integration of three major areas of long-term forecasting: socio-economic, scientific-technological, and economy-climate. It is shown that implementation of the Critical Project can be useful not only for substantiation of decisions related to climate policy, but also for mechanisms used to form a long-term strategy of socio-economic development. © 2023, Pleiades Publishing, Ltd.