Antioxidant polyphenol-rich extracts from the medicinal plants Antirhea borbonica, Doratoxylon apetalum and Gouania mauritiana protect 3T3-L1 preadipocytes against H2O2, TNFα and LPS inflammatory mediators by regulating the expression of superoxide dismutase and NF-κB genes

被引：0

作者：

Méry Marimoutou

Fanny Le Sage

Jacqueline Smadja

Christian Lefebvre d’Hellencourt

Marie-Paule Gonthier

Christine Robert-Da Silva

机构：

[1] Inserm U1188 - Université de La Réunion,UMR Diabète athérothrombose Thérapies Réunion Océan Indien

[2] Plateforme CYROI,undefined

[3] Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments,undefined

[4] EA 2212,undefined

[5] Université de La Réunion,undefined

来源：

Journal of Inflammation | / 12卷

关键词：

Obesity; Oxidative stress; Inflammation; Antioxidant strategies; Plant polyphenols;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 252 条

[11] Berg A(2005)Inflammation, stress, and diabetes J Clin Investig 115 1111-9
[12] Iyengar P(2007)The Emerging Role of Adipokines as Mediators of Cardiovascular Function: Physiologic and Clinical Perspectives Trends in Cardiovascular Medicine 17 275-83
[13] Lam T(2006)Microbial ecology: human gut microbes associated with obesity Nature (London) 444 1022-3
[14] Giacca A(2012)Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity Gut Microbes 3 279-88
[15] Combs T(2000)The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes J Biol Chem 275 24255-63
[16] Rigoulet M(2007)Presence of functional TLR2 and TLR4 on human adipocytes Histochem Cell Biol 127 131-7
[17] Yoboue E(2004)Adipocyte differentiation induces dynamic changes in NF-kB expression and activity Am J Physiol Endocrinol Metab 287 E1178-88
[18] Devin A(2000)Dietary intake and bioavailability of polyphenols J Nutr 130 2073S-85
[19] de Ferranti S(2013)Modulation of adipose tissue inflammation by bioactive food compounds J Nutr Biochem 24 613-23
[20] Mozaffarian D(2014)Novel insights of dietary polyphenols and obesity J Nutr Biochem 25 1-18