Kinomic profiling of glioblastoma cells reveals PLCG1 as a target in restricted glucose

[1] Ohgaki H(2005)Epidemiology and etiology of gliomas Acta Neuropathol 109 93-108

[2] Kleihues P(2014)Standards of care and novel approaches in the management of glioblastoma multiforme Chinese journal of cancer 33 32-39

[3] Hottinger AF(2009)Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial The Lancet Oncology 10 459-466

[4] Stupp R(2015)Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines Biochim Biophys Acta 1850 722-732

[5] Homicsko K(2005)Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 987-996

[6] Stupp R(2014)GBM's multifaceted landscape: highlighting regional and microenvironmental heterogeneity Neuro-Oncology 16 1167-1175

[7] Hegi ME(2010)Metabolic microenvironment of tumor cells: a key factor in malignant progression Exp Oncol 32 125-127

[8] Mason WP(1994)Blood flow and metabolic microenvironment of brain tumors J Neuro-Oncol 22 261-267

[9] van den Bent MJ(1989)Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review Cancer Res 49 6449-6465

[10] Taphoorn MJ(2013)Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake Nat Neurosci 16 1373-1382

[1] Ohgaki H(2005)Epidemiology and etiology of gliomas Acta Neuropathol 109 93-108

[2] Kleihues P(2014)Standards of care and novel approaches in the management of glioblastoma multiforme Chinese journal of cancer 33 32-39

[3] Hottinger AF(2009)Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial The Lancet Oncology 10 459-466

[4] Stupp R(2015)Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines Biochim Biophys Acta 1850 722-732

[5] Homicsko K(2005)Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 987-996

[6] Stupp R(2014)GBM's multifaceted landscape: highlighting regional and microenvironmental heterogeneity Neuro-Oncology 16 1167-1175

[7] Hegi ME(2010)Metabolic microenvironment of tumor cells: a key factor in malignant progression Exp Oncol 32 125-127

[8] Mason WP(1994)Blood flow and metabolic microenvironment of brain tumors J Neuro-Oncol 22 261-267

[9] van den Bent MJ(1989)Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review Cancer Res 49 6449-6465

[10] Taphoorn MJ(2013)Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake Nat Neurosci 16 1373-1382