The CDK4–pRB–E2F1 pathway controls insulin secretion

被引：0
作者：
Jean-Sébastien Annicotte
Emilie Blanchet
Carine Chavey
Irena Iankova
Safia Costes
Said Assou
Jacques Teyssier
Stéphane Dalle
Claude Sardet
Lluis Fajas
机构：
[1] INSERM,
[2] U834,undefined
[3] IRCM,undefined
[4] Institut de Recherche en Cancérologie de Montpellier,undefined
[5] Montpellier,undefined
[6] F-34298,undefined
[7] France. INSERM,undefined
[8] U896,undefined
[9] Montpellier,undefined
[10] F-34298,undefined
[11] France. Univ Montpellier1,undefined
[12] Montpellier,undefined
[13] F-34298,undefined
[14] France; CRLC Val d'Aurelle Paul Lamarque,undefined
[15] Montpellier,undefined
[16] F-34298,undefined
[17] France,undefined
[18] CRLC Val d'Aurelle Paul Lamarque,undefined
[19] Montpellier,undefined
[20] F-34298,undefined
[21] France,undefined
[22] CNRS,undefined
[23] UMR5203,undefined
[24] Institut de Génomique Fonctionnelle,undefined
[25] Montpellier,undefined
[26] F-34094,undefined
[27] France. INSERM,undefined
[28] U661,undefined
[29] Equipe AVENIR,undefined
[30] Montpellier,undefined
[31] F-34094,undefined
[32] France. Univ Montpellier1,undefined
[33] 2,undefined
[34] Centre Hospitalier Universitaire,undefined
[35] Institute for Research in Biotherapy,undefined
[36] Hôpital Saint Eloi,undefined
[37] Institut de Génétique Moléculaire,undefined
[38] CNRS,undefined
[39] UMR5535,undefined
[40] Univ Montpellier 2,undefined
[41] Centre Hospitalier Universitaire Arnaud de Villeneuve,undefined
来源：
Nature Cell Biology | 2009年 / 11卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
The Cdk4–pRb–E2F1 pathway is shown to have a role in insulin secretion in b cells by controlling the expression of a subunit of the K+ATP channel through E2F1 binding to its promoter.
引用
收藏
页码：1017 / 1023
页数：6
相关论文
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