Genome-wide analysis of the replication program in mammals

被引：0
作者：
Shlomit Farkash-Amar
Itamar Simon
机构：
[1] The Hebrew University–Hadassah Medical School,Department of Microbiology and Molecular Genetics, The Institute for Medical Research—Israel–Canada
来源：
Chromosome Research | 2010年 / 18卷
关键词：
time of replication; genomics; transcription; epigenetic; genomic stability; Microarrays;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Microarray technology has facilitated the research of eukaryotic DNA replication on a genome-wide scale. Recent studies have shed light on the association between time of replication and chromosome structure, on the organization principles of the replication program, and on the correlation between replication timing and transcription. In this review, we summarize various genomic measurement approaches and the biological insights achieved through applying them in the study of the mammalian replication program.
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页码：115 / 125
页数：10
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