Design, Synthesis, In Vitro Cytotoxicity, ADME Prediction, and Molecular Docking Study of Benzimidazole-Linked Pyrrolone and N-Benzylpyrrolone Derivatives

被引：0

作者：

A. Husain

M. Bhutani

S. Parveen

S. A. Khan

A. Ahmad

M. A. Iqbal

机构：

[1] Department of Pharmaceutical Chemistry,

[2] School of Pharmaceutical Education and Research,undefined

[3] Jamia Hamdard,undefined

[4] Chemistry Department,undefined

[5] Faculty of Science,undefined

[6] Taibah University,undefined

[7] Yanbu Branch,undefined

[8] Department of Chemistry,undefined

[9] School of Chemical and Life Sciences,undefined

[10] Jamia Hamdard,undefined

[11] College of Pharmacy,undefined

[12] National University of Science and Technology,undefined

[13] Health Information Technology Department,undefined

[14] Faculty of Applied Studies,undefined

[15] King Abdulaziz University,undefined

来源：

Russian Journal of Organic Chemistry | 2022年 / 58卷

关键词：

heterocyclics; pyrrolone; anticancer activity; VEGFR-2; molecular docking;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：1438 / 1450

页数：12

共 190 条

[1] Ahn Y.(2007)undefined Early Hum. Dev. 83 255-undefined
[2] Jun Y.(2012)undefined Eur. J. Med. Chem. 54 855-undefined
[3] Rashid M.(2017)undefined Best Pract. Res., Clin. Endocrinol. Metab. 31 335-undefined
[4] Husain A.(2017)undefined Anticancer Drugs 28 362-undefined
[5] Mishra R.(2011)undefined Science 331 1559-undefined
[6] Hadoux J.(2008)undefined Nat. Clin. Pract. Oncol. 5 206-undefined
[7] Schlumberger M.(2017)undefined J. Mol. Struct. 1133 66-undefined
[8] Karabajakian A.(2016)undefined Eur. J. Med. Chem. 124 649-undefined
[9] Toussaint P.(2019)undefined Molecules 24 3259-undefined
[10] Neidhardt E.M.(2010)undefined Cell 25 1117-undefined