Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment

被引：0

作者：

Hao Yuan Kueh

Mary A Yui

Kenneth K H Ng

Shirley S Pease

Jingli A Zhang

Sagar S Damle

George Freedman

Sharmayne Siu

Irwin D Bernstein

Michael B Elowitz

Ellen V Rothenberg

机构：

[1] California Institute of Technology,Division of Biology and Biological Engineering

[2] Fred Hutchinson Cancer Research Center,Clinical Research Division

[3] Howard Hughes Medical Institute,undefined

[4] California Institute of Technology,undefined

[5] Present addresses: Department of Bioengineering,undefined

[6] University of Washington,undefined

[7] Seattle,undefined

[8] Washington,undefined

[9] USA (H.Y.K.),undefined

[10] Genentech,undefined

[11] South San Francisco,undefined

[12] California,undefined

[13] USA (J.A.Z.),undefined

[14] Department of Bioinformatics,undefined

[15] Antisense Drug Discovery,undefined

[16] Isis Pharmaceuticals,undefined

[17] Carlsbad,undefined

[18] California,undefined

[19] USA (S.S.D.),undefined

[20] and Department of Pediatrics,undefined

[21] University of California,undefined

[22] San Francisco School of Medicine,undefined

[23] San Francisco,undefined

[24] California,undefined

[25] USA (G.F.).,undefined

来源：

Nature Immunology | 2016年 / 17卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Kueh, Rothenberg and colleagues describe distinct, asynchronous and stage-specific mechanisms of T cell commitment mediated by the transcription factors Notch, TCF-1, GATA-3 and Runx1.

引用

页码：956 / 965

页数：9

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