Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment

被引：0
|
作者：
Hao Yuan Kueh
Mary A Yui
Kenneth K H Ng
Shirley S Pease
Jingli A Zhang
Sagar S Damle
George Freedman
Sharmayne Siu
Irwin D Bernstein
Michael B Elowitz
Ellen V Rothenberg
机构：
[1] California Institute of Technology,Division of Biology and Biological Engineering
[2] Fred Hutchinson Cancer Research Center,Clinical Research Division
[3] Howard Hughes Medical Institute,undefined
[4] California Institute of Technology,undefined
[5] Present addresses: Department of Bioengineering,undefined
[6] University of Washington,undefined
[7] Seattle,undefined
[8] Washington,undefined
[9] USA (H.Y.K.),undefined
[10] Genentech,undefined
[11] South San Francisco,undefined
[12] California,undefined
[13] USA (J.A.Z.),undefined
[14] Department of Bioinformatics,undefined
[15] Antisense Drug Discovery,undefined
[16] Isis Pharmaceuticals,undefined
[17] Carlsbad,undefined
[18] California,undefined
[19] USA (S.S.D.),undefined
[20] and Department of Pediatrics,undefined
[21] University of California,undefined
[22] San Francisco School of Medicine,undefined
[23] San Francisco,undefined
[24] California,undefined
[25] USA (G.F.).,undefined
来源：
Nature Immunology | 2016年 / 17卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Kueh, Rothenberg and colleagues describe distinct, asynchronous and stage-specific mechanisms of T cell commitment mediated by the transcription factors Notch, TCF-1, GATA-3 and Runx1.
引用
收藏
页码：956 / 965
页数：9
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