Titanocene(III) chloride mediated radical induced addition-elimination route to the synthesis of racemic and optically active trisubstituted tetrahydrofurans: Formal synthesis of magnofargesin and 7′-epimagnofargesin

被引：0
|
作者：
P CHAKRABORTY
S K MANDAL
S C ROY
机构：
[1] Indian Association for the Cultivation of Science,Department of Organic Chemistry
[2] Saldiha College,Department of Chemistry
来源：
Journal of Chemical Sciences | 2016年 / 128卷
关键词：
Titanocene(III) chloride; radical; tetrahydrofurans; synthesis; furano lignans;
D O I：
暂无
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学科分类号：
摘要：
Titanocene(III) Chloride mediated radical induced synthesis of 4-benzylidene substituted tetrahydrofuran, a typical lignan skeleton, has been accomplished in good yield through addition-elimination route in racemic as well as in optically active forms. The method has been applied to the synthesis of furano lignans, magnofargesin (1) and 7′-epimagnofargesin (2) in optically active forms.
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页码：1067 / 1079
页数：12
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