The effect of clodronate on a mevalonate kinase deficiency cellular model

被引:0
作者
Valentina Zanin
Annalisa Marcuzzi
Elisa Piscianz
Josef Vuch
Anna Monica Bianco
Lorenzo Monasta
Giuliana Decorti
Sergio Crovella
机构
[1] Institute for Maternal and Child Health–IRCCS “Burlo Garofolo”,
[2] University of Trieste,undefined
来源
Inflammation Research | 2012年 / 61卷
关键词
Mevalonate kinase deficiency; Clodronate; Apoptosis; Nitric oxide;
D O I
暂无
中图分类号
学科分类号
摘要
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页码:1363 / 1367
页数:4
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[1]  
Kuijk LM(2008)HMG-CoA reductase inhibition induces IL-1beta release through Rac1/PI3 K/PKB-dependent caspase-1 activation Blood 112 3563-3573
[2]  
Beekman JM(2006)A role for geranylgeranylation in interleukin-1beta secretion Arthritis Rheum 54 3690-3695
[3]  
Koster J(2008)Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency Pediatr Res 64 177-182
[4]  
Mandey SH(2005)Effect of etanercept and anakinra on inflammatory attacks in the hyper-IgD syndrome: introducing a vaccination provocation model Neth J Med 63 260-264
[5]  
Kuijk LM(2011)Defect in mevalonate pathway induces pyroptosis in Raw 264.7 murine monocytes Apoptosis 16 882-888
[6]  
Frenkel J(2010)Natural isoprenoids inhibit LPS induced-production of cytokines and nitric oxide in aminobisphosphonate-treated monocytes Int Immunopharmacol 10 639-642
[7]  
Marcuzzi A(2006)Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis J Inherit Metab Dis 29 763-310
[8]  
Pontillo A(2008)Long-term follow-up, clinical features and quality of life in a series of 103 patients with hyperimmunoglobulinemia D syndrome Medicine. 87 301-128
[9]  
De Leo L(2010)Pro-IL-1beta accumulation in macrophages by alendronate and its prevention by clodronate Toxicol Lett 199 123-510
[10]  
Bodar EJ(2010)Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches Pharmacol Res 61 506-118