Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy

被引:0
作者
Neena Lala-Tabbert
Rim Lejmi-Mrad
Kristen Timusk
Marina Fukano
Janelle Holbrook
Martine St-Jean
Eric C. LaCasse
Robert G. Korneluk
机构
[1] Children’s Hospital of Eastern Ontario Research Institute,Apoptosis Research Centre
[2] University of Ottawa,Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine
[3] University of Ottawa,Department of Cellular and Molecular Medicine, Faculty of Medicine
来源
Skeletal Muscle | / 9卷
关键词
cIAP1; NF-κB; Muscle atrophy; MuRF1; Atrogin-1; Denervation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 176 条
  • [1] Cohen S(2015)Muscle wasting in disease: molecular mechanisms and promising therapies Nat Rev Drug Discov 14 58-74
  • [2] Nathan JA(2004)Molecular mechanisms of muscle atrophy Cell. 119 907-910
  • [3] Goldberg AL(2001)Skeletal muscle atrophy identification of ubiquitin ligases required for skeletal muscle atrophy Science (80- ). 1704 1704-1708
  • [4] Mckinnell IW(2001)Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy Proc Natl Acad Sci U S A 98 14440-14445
  • [5] Rudnicki MA(2004)IKKβ/NF-κB activation causes severe muscle wasting in mice Cell. 119 285-298
  • [6] Bodine SC(2006)Targeted ablation of IKK2 improves skeletal muscle strength , maintains mass , and promotes regeneration J Clin Invest 116 2945-2954
  • [7] Lai VK(2008)NF-κB signaling in skeletal muscle: prospects for intervention in muscle diseases J Mol Med 86 747-759
  • [8] Nunez L(2000)NF-κB mediates the protein loss induced by TNF-α in differentiated skeletal muscle myotubes Am J Phys 279 R1165-R1170
  • [9] Clarke BA(2010)The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice J Cell Biol 188 833-849
  • [10] Gomes MD(2009)The IkB kinases IKKalpha and IKKbeta are necessary and sufficient for skeletal muscle atrophy FASEB J 23 362-370