Somatic copy number alteration and fragmentation analysis in circulating tumor DNA for cancer screening and treatment monitoring in colorectal cancer patients

被引：0
|
作者：
Ariane Hallermayr
Tobias Wohlfrom
Verena Steinke-Lange
Anna Benet-Pagès
Florentine Scharf
Ellen Heitzer
Ulrich Mansmann
Christopher Haberl
Maike de Wit
Holger Vogelsang
Markus Rentsch
Elke Holinski-Feder
Julia M. A. Pickl
机构：
[1] MGZ – Medizinisch Genetisches Zentrum,Institute for Medical Information Processing, Biometry, and Epidemiology –IBE
[2] Pettenkofer School of Public Health,Medizinische Klinik Und Poliklinik IV, Campus Innenstadt
[3] LMU Munich,Institute of Neurogenomics
[4] Klinikum Der Universität München,Institute of Human Genetics, Diagnostic and Research Center for Molecular Biomedicine (Austria)
[5] Helmholtz Zentrum München - German Research Center for Environmental Health,Department of Oncology and Hematology
[6] Medical University of Graz,Department of Hematology, Oncology and Palliative Medicine
[7] BioTechMed-Graz,Department of Oncology
[8] Christian Doppler Laboratory for Liquid Biopsies for Early Detection of Cancer,Department of General, Visceral, Thoracic and Endocrine Surgery
[9] Barmherzige Brüder,Department of General, Visceral and Thorax Surgery
[10] Klinikum St. Elisabeth,Department of General, Visceral, Vascular and Transplant Surgery
[11] Vivantes Klinikum Neukoelln,undefined
[12] Vivantes Auguste-Viktoria-Klinikum,undefined
[13] Klinikum Garmisch-Partenkirchen,undefined
[14] Teaching Hospital,undefined
[15] Ludwig Maximilian University Munich,undefined
[16] Klinikum Ingolstadt,undefined
[17] University Hospital Munich,undefined
[18] Ludwig-Maximilians University of Munich,undefined
来源：
Journal of Hematology & Oncology | / 15卷
关键词：
ctDNA; Colorectal cancer; Liquid biopsy; Whole-genome sequencing; Somatic copy number alterations; cfDNA fragmentation; Chromatin signatures;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Somatic Copy-Number Alterations in Plasma Circulating Tumor DNA from Advanced EGFR-Mutated Lung Adenocarcinoma Patients
    Buder, Anna
    Heitzer, Ellen
    Waldispuehl-Geigl, Julie
    Weber, Sabrina
    Moser, Tina
    Hochmair, Maximilian J.
    Hackner, Klaus
    Errhalt, Peter
    Setinek, Ulrike
    Filipits, Martin
    BIOMOLECULES, 2021, 11 (05)
  • [32] Somatic Copy Number Alterations in Colorectal Cancer Lead to a Differentially Expressed ceRNA Network (ceRNet)
    Herrera-Orozco, Hector
    Garcia-Castillo, Veronica
    Lopez-Urrutia, Eduardo
    Martinez-Gutierrez, Antonio Daniel
    Perez-Yepez, Eloy
    Millan-Catalan, Oliver
    de Leon, David Cantu
    Lopez-Camarillo, Cesar
    Jacobo-Herrera, Nadia J.
    Rodriguez-Dorantes, Mauricio
    Ramos-Payan, Rosalio
    Perez-Plasencia, Carlos
    CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023, 45 (12) : 9549 - 9565
  • [33] Detection of circulating tumor DNA by tumor-informed whole-genome sequencing enables prediction of recurrence in stage III colorectal cancer patients
    Frydendahl, Amanda
    Nors, Jesper
    Rasmussen, Mads H.
    Henriksen, Tenna V.
    Nesic, Marijana
    Reinert, Thomas
    Afterman, Danielle
    Lauterman, Tomer
    Kuzman, Maja
    Gonzalez, Santiago
    Glavas, Dunja
    Smadback, James
    Maloney, Dillon
    Levativ, Jurica
    Yahalom, Michael
    Ptashkin, Ryan
    Tavassoly, Iman
    Donenhirsh, Zohar
    White, Eric
    Kandasamy, Ravi
    Alon, Ury
    Nordentoft, Iver
    Lindskrog, Sia V.
    Dyrskjot, Lars
    Jaensch, Claudia
    Love, Uffe S.
    Andersen, Per V.
    Thorlacius-Ussing, Ole
    Iversen, Lene H.
    Gotschalck, Kare A.
    Zviran, Asaf
    Oklander, Boris
    Andersen, Claus L.
    EUROPEAN JOURNAL OF CANCER, 2024, 211
  • [34] The Use of Circulating Tumor DNA to Monitor and Predict Response to Treatment in Colorectal Cancer
    Reece, Mifanwy
    Saluja, Hariti
    Hollington, Paul
    Karapetis, Christos S.
    Vatandoust, Sina
    Young, Graeme P.
    Symonds, Erin L.
    FRONTIERS IN GENETICS, 2019, 10
  • [35] Cancer therapy monitoring in xenografts by quantitative analysis of circulating tumor DNA
    Gorges, Tobias M.
    Schiller, Johanna
    Schmitz, Arndt
    Schuetzmann, Daniel
    Schatz, Christoph
    Zollner, Thomas M.
    Krahn, Thomas
    von Ahsen, Oliver
    BIOMARKERS, 2012, 17 (06) : 498 - 506
  • [36] Circulating tumor DNA detection: A potential tool for colorectal cancer management
    Li, Huizi
    Jing, Changwen
    Wu, Jianzhong
    Ni, Jie
    Sha, Huanhuan
    Xu, Xiaoyue
    Du, Yuanyuan
    Lou, Rui
    Dong, Shuchen
    Feng, Jifeng
    ONCOLOGY LETTERS, 2019, 17 (02) : 1409 - 1416
  • [37] Circulating tumor DNA methylation marker MYO1-G for diagnosis and monitoring of colorectal cancer
    Wu-Hao Lin
    Jian Xiao
    Zi-Yi Ye
    Da-Liang Wei
    Xiao-Hui Zhai
    Rui-Hua Xu
    Zhao-Lei Zeng
    Hui-Yan Luo
    Clinical Epigenetics, 2021, 13
  • [38] Circulating Tumor DNA as a Novel Biomarker Optimizing Chemotherapy for Colorectal Cancer
    Osumi, Hiroki
    Shinozaki, Eiji
    Yamaguchi, Kensei
    CANCERS, 2020, 12 (06) : 1 - 11
  • [39] Utility of circulating tumor cells and DNA in the management of advanced colorectal cancer
    Pan, Xiaohong
    Zhang, Xiaoli
    FUTURE ONCOLOGY, 2020, 16 (18) : 1289 - 1300
  • [40] Circulating Tumor DNA Is Capable of Monitoring the Therapeutic Response and Resistance in Advanced Colorectal Cancer Patients Undergoing Combined Target and Chemotherapy
    Cao, Hua
    Liu, Xinyi
    Chen, Yixin
    Yang, Pan
    Huang, Tanxiao
    Song, Lele
    Xu, Ruilian
    FRONTIERS IN ONCOLOGY, 2020, 10
12345