Somatic copy number alteration and fragmentation analysis in circulating tumor DNA for cancer screening and treatment monitoring in colorectal cancer patients

被引：0
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作者：
Ariane Hallermayr
Tobias Wohlfrom
Verena Steinke-Lange
Anna Benet-Pagès
Florentine Scharf
Ellen Heitzer
Ulrich Mansmann
Christopher Haberl
Maike de Wit
Holger Vogelsang
Markus Rentsch
Elke Holinski-Feder
Julia M. A. Pickl
机构：
[1] MGZ – Medizinisch Genetisches Zentrum,Institute for Medical Information Processing, Biometry, and Epidemiology –IBE
[2] Pettenkofer School of Public Health,Medizinische Klinik Und Poliklinik IV, Campus Innenstadt
[3] LMU Munich,Institute of Neurogenomics
[4] Klinikum Der Universität München,Institute of Human Genetics, Diagnostic and Research Center for Molecular Biomedicine (Austria)
[5] Helmholtz Zentrum München - German Research Center for Environmental Health,Department of Oncology and Hematology
[6] Medical University of Graz,Department of Hematology, Oncology and Palliative Medicine
[7] BioTechMed-Graz,Department of Oncology
[8] Christian Doppler Laboratory for Liquid Biopsies for Early Detection of Cancer,Department of General, Visceral, Thoracic and Endocrine Surgery
[9] Barmherzige Brüder,Department of General, Visceral and Thorax Surgery
[10] Klinikum St. Elisabeth,Department of General, Visceral, Vascular and Transplant Surgery
[11] Vivantes Klinikum Neukoelln,undefined
[12] Vivantes Auguste-Viktoria-Klinikum,undefined
[13] Klinikum Garmisch-Partenkirchen,undefined
[14] Teaching Hospital,undefined
[15] Ludwig Maximilian University Munich,undefined
[16] Klinikum Ingolstadt,undefined
[17] University Hospital Munich,undefined
[18] Ludwig-Maximilians University of Munich,undefined
来源：
Journal of Hematology & Oncology | / 15卷
关键词：
ctDNA; Colorectal cancer; Liquid biopsy; Whole-genome sequencing; Somatic copy number alterations; cfDNA fragmentation; Chromatin signatures;
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