Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids

被引：0
|
作者：
Alison L Groeger
Chiara Cipollina
Marsha P Cole
Steven R Woodcock
Gustavo Bonacci
Tanja K Rudolph
Volker Rudolph
Bruce A Freeman
Francisco J Schopfer
机构：
[1] University of Pittsburgh,Department of Pharmacology & Chemical Biology
[2] Fondazione Ri.MED,undefined
[3] Piazza Sett'Angeli 10,undefined
[4] Cardiovascular Research Center,undefined
[5] University Heart Center Hamburg,undefined
来源：
Nature Chemical Biology | 2010年 / 6卷
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学科分类号：
摘要：
Six new species of electrophilic lipids identified in activated macrophages are derived from COX-2 action on ω-3 fatty acids and mediate anti-inflammatory and anti-oxidant activities.[graphic not available: see fulltext]
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页码：433 / 441
页数：8
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