Langerhans cell histiocytosis on the penis: A case report

被引:5
作者
Hagiuda J. [1 ]
Ueno M. [1 ]
Ashimine S. [1 ]
Kuroda I. [1 ]
Ishizawa K. [2 ]
Deguchi N. [1 ]
机构
[1] Department of Urology, Saitama Medical University, Saitama
[2] Department of Pathology, Saitama Medical University, Saitama
关键词
Cervical Intraepithelial Neoplasia; Femur Bone; Eosinophilic Granuloma; Birbeck Granule; Pale Cytoplasm;
D O I
10.1186/1471-2490-6-28
中图分类号
学科分类号
摘要
Background: Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs. A few cases of Langerhans cell histiocytosis on the penis have been reported in the literature. We present a case of Langerhans cell histiocytosis on the penis and review the similar cases in the literature. Case presentation: The patient was a 13-year-old boy who had a history of lymph node, femur bone, and pituitary-thalmic axis lesions from Langerhans cell histiocytosis who noticed a painful nodule on the prepuce of his penis. The histological and immunohistochemical examination fulfilled the criteria of Langerhans cell histiocytosis. Conclusion: We herein describe the case reported of Langerhans cell histiocytosis on the penis. © 2006 Hagiuda et al; licensee BioMed Central Ltd.
引用
收藏
相关论文
共 11 条
[1]  
Histiocytosis syndromes in children, Lancet, 1, 8526, pp. 208-209, (1987)
[2]  
Howarth D.M., Gilchrist G.S., Mullan B.P., Wiseman G.A., Edmonson J.H., Schomberg P.J., Langerhans cell histiocytosis
[3]  
diagnosis, natural history, management, and outcome, Cancer, 85, pp. 2278-2290, (1999)
[4]  
Myers D.A., Strandjord S.E., Marcus Jr. R.B., Histiocytosis X presenting as a primary penile lesion, J Urol, 126, pp. 268-269, (1981)
[5]  
Caputo R., Gianotti R., Monti M., Nodular 'pure' mococutaneous histiocytosis X in an adult, Arch Dermatol, 123, pp. 1274-1275, (1987)
[6]  
Yokota T., Aga Y., Miki H., Oomori M., A case of histiocytosis X of the penis, Jpn J Urol, 81, pp. 1904-1907, (1990)
[7]  
Meehan S.A., Smoller B.R., Cutaneous Langerhans cell histiocytosis of the genitalia in the elderly: A report of three cases, J Cutan Pathol, 25, pp. 370-374, (1998)
[8]  
Seseke F., Kugler A., Hermanns M., Zoller G., Kallerhoff M., Ringert R.H., Langerhans cell histiocytosis of the penis, Urologe, 38, pp. 42-45, (1999)
[9]  
Maekawa Y., Kogushi H., A case of Langerhans cell histiocytosis on the foreskin and external auditory meatus, J Pediat Dermatol, 23, pp. 35-38, (2004)
[10]  
Singh A., Prieto V., Czelusta A., Czelusta A., McClain K., Duvic M., Adult Langerhans cell histiocytosis limited to the skin, Dermatology, 207, pp. 157-161, (2003)