Molecular mechanism of the spontaneous segregation of enantiomers in liquid nanoblobs

被引：0
|
作者：
D. V. Zlenko
M. A. Tregubova
S. V. Stovbun
机构：
[1] Lomonosov Moscow State University,Semenov Institute of Chemical Physics
[2] Russian Academy of Sciences,undefined
来源：
Russian Journal of Physical Chemistry B | 2017年 / 11卷
关键词：
chirality; spontaneous segregation; molecular modeling; enantiomer excess;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
At present, the problem of spontaneous segregation has no satisfactory theoretical description. The main difficulty is a very low probability of the spontaneous formation of a chirally pure nucleus in a racemic mixture if the enantioselectivity energy is below (10–12)kT, which does not correspond to reality. In this paper, we propose a mechanism of the enhancement of enantioselectivity in the chiral phase nucleus, which circumvents the problem of the low probability of its formation.
引用
收藏
页码：343 / 347
页数：4
相关论文
共 50 条
  • [1] Molecular mechanism of the spontaneous segregation of enantiomers in liquid nanoblobs
    Zlenko, D. V.
    Tregubova, M. A.
    Stovbun, S. V.
    RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B, 2017, 11 (02) : 343 - 347
  • [2] Molecular Mechanism of Enantioselective Inhibition of Acetolactate Synthase by Imazethapyr Enantiomers
    Zhou, Qingyan
    Zhang, Na
    Zhang, Cheng
    Huang, Lidong
    Niu, Yaofang
    Zhang, Yongsong
    Liu, Weiping
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (07) : 4202 - 4206
  • [3] Molecular Docking of Chiral Drug Enantiomers With Different Bioactivities
    Semenova, Ekaterina V.
    Belova, Ekaterina V.
    Sulimov, Alexey V.
    Sulimov, Vladimir B.
    CHIRALITY, 2024, 36 (09)
  • [4] Spontaneous Discrimination of Polycyclic Aromatic Hydrocarbon (PAH) Enantiomers on a Metal Surface
    Otero, Gonzalo
    Biddau, Giulio
    Ozaki, Taisuke
    Gomez-Lor, Berta
    Mendez, Javier
    Perez, Ruben
    Angel Martin-Gago, Jose
    CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (47) : 13920 - 13924
  • [5] Spontaneous Resolution of Enantiomers by Crystallization: Insights from Computed Crystal Energy Landscapes
    D'Oria, Emiliana
    Karamertzanis, Panagiotis G.
    Price, Sarah L.
    CRYSTAL GROWTH & DESIGN, 2010, 10 (04) : 1749 - 1756
  • [6] Configurationally stable molecular propellers:: First resolution of residual enantiomers
    Benincori, Tiziana
    Celentano, Giuseppe
    Pilati, Tullio
    Ponti, Alessandro
    Rizzo, Simona
    Sannicolo, Francesco
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (37) : 6193 - 6196
  • [7] Chiral molecular recognition for the detection and analysis of enantiomers by mass spectrometric methods
    Schug, KA
    Lindner, W
    JOURNAL OF SEPARATION SCIENCE, 2005, 28 (15) : 1932 - 1955
  • [8] Pasteurian Segregation on a Surface Imaged In Situ at the Molecular Level
    Xu, Hong
    Saletra, Wojciech J.
    Iavicoli, Patrizia
    Van Averbeke, Bernard
    Ghijsens, Elke
    Mali, Kunal S.
    Schenning, Albertus P. H. J.
    Beljonne, David
    Lazzaroni, Roberto
    Amabilino, David B.
    De Feyter, Steven
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (48) : 11981 - 11985
  • [9] Molecular recognition of sec-alcohol enantiomers by Candida antarctica lipase B
    Rotticci, D
    Haeffner, F
    Orrenius, C
    Norin, T
    Hult, K
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 1998, 5 (1-4) : 267 - 272
  • [10] Separation of Enantiomers of sec-Butyl Carboxylicates on β-Cyclodextrin Derivatives and Chiral Recognization Mechanism
    Shi Jie-Hua
    Ye Yan
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2010, 38 (10) : 1450 - 1456
12345