Age determines the prognostic role of the cancer stem cell marker aldehyde dehydrogenase-1 in breast cancer

被引:0
作者
J Sven D Mieog
Esther M de Kruijf
Esther Bastiaannet
Peter JK Kuppen
Anita Sajet
Anton JM de Craen
Vincent THBM Smit
Cornelis JH van de Velde
Gerrit-Jan Liefers
机构
[1] Leiden University Medical Center,Department of Surgery
[2] Leiden University Medical Center,Department of Gerontology & Geriatrics
[3] Leiden University Medical Center,Department of Pathology
来源
BMC Cancer | / 12卷
关键词
Breast cancer; Age; ALDH1; Prognostic factor Part of this work has been presented at the American Association for Cancer Research (AACR) Annual Meeting 2011;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 150 条
  • [1] Anders CK(2009)Breast cancer before age 40 years Semin Oncol 36 237-249
  • [2] Johnson R(1995)Genetic evolution of breast cancers. III: age-dependent variations in the correlations between biological indicators of prognosis Breast Cancer Res Treat 34 25-33
  • [3] Litton J(2000)Tumor characteristics and clinical outcome of elderly women with breast cancer J Natl Cancer Inst 92 550-556
  • [4] Phillips M(2011)The impact of age on outcome in early-stage breast cancer Semin Radiat Oncol 21 26-34
  • [5] Bleyer A(2009)Qualitative age interactions in breast cancer studies: mind the gap J Clin Oncol 27 5308-5311
  • [6] Remvikos Y(2010)Breast cancer in elderly compared to younger patients in The Netherlands: stage at diagnosis, treatment and survival in 127,805 unselected patients Breast Cancer Res Treat 124 801-807
  • [7] Magdelenat H(2003)Prospective identification of tumorigenic breast cancer cells Proc Natl Acad Sci USA 100 3983-3988
  • [8] Dutrillaux B(2008)Alpha-6 integrin is necessary for the tumourigenicity of a stem cell-like subpopulation within the MCF7 breast cancer cell line Int J Cancer 122 298-304
  • [9] Diab SG(2007)ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome Cell Stem Cell 1 555-567
  • [10] Elledge RM(2008)Brca1 breast tumors contain distinct CD44+/CD24- and CD133+ cells with cancer stem cell characteristics Breast Cancer Res 10 R10-108