Impact of COVID-19 on antimicrobial stewardship activities in Italy: a region-wide assessment

被引:2
|
作者
Vicentini, Costanza [1 ]
Corcione, Silvia [2 ]
Lo Moro, Giuseppina [1 ]
Mara, Alessandro [1 ]
De Rosa, Francesco Giuseppe [2 ]
Zotti, Carla Maria [1 ]
机构
[1] Univ Turin, Dept Publ Hlth & Pediat, Via Santena 5 Bis, I-10126 Turin, Italy
[2] Univ Turin, Dept Med Sci, Infect Dis, Turin, Italy
关键词
Antimicrobial stewardship; Quality indicators; Antimicrobial usage; Antimicrobial resistance; Quality improvement; Italy; COVID-19; Pandemic; EPIDEMIC;
D O I
10.1186/s13756-024-01407-3
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background In the region of Piedmont, in Northern Italy, formal monitoring of antimicrobial stewardship (AMS) programs has been in place since 2012. The objective of our study was to provide an updated assessment of AMS programs operating in our region, and to assess the impact of the COVID-19 pandemic on stewardship activities.Methods A retrospective observational study was conducted to investigate AMS programs implemented in acute-care trusts participating in a broader healthcare-associated infections and antimicrobial resistance (AMR) prevention and control program, promoted by the regional health department. Within this program, structure, process, and outcome indicators of AMS programs were investigated, using a previously developed scoring system. Differences between scores prior to (2019) and during the pandemic (2021) were assessed. Linear regression was used to assess whether the 5-year trends (2017-2021) in outcome measures in relation to structure and process scores were statistically significant. Compound annual growth rates (CAGR) for each outcome were calculated to illustrate changes in outcome rates over time.Results All public trusts in the Region (20) and a small number of private institutions (3) provided data for this study. A modest, non-significant improvement was found for 2021 structure, process, and total scores compared to respective 2019 scores. A significant improvement was found concerning the definition of a formal mission statement, whereas significantly less trusts included monitoring adherence to antimicrobial policy or treatment guidelines in their programs. Overall consumption of antibiotics for systemic use saw an increase in 2021, with 2021 recording the highest median overall consumption compared to all previous years considered in this study. Methicillin-resistant Staphylococcus aureus (MRSA) and carbapenem-resistant enterobacteria (CRE) rates decreased over the 5-year period. Significant downwards trends in MRSA rates were identified for high-outlier structure and process groups.Conclusions Results of this study suggest AMS programs in Piedmont were not set back following the pandemic. This outcome was possible thanks to well-established programs, coordinated within a regional framework. Continued efforts should be dedicated to supporting AMS programs and contrasting AMR, even when the focus is shifted towards other public health emergencies.
引用
收藏
页数:9
相关论文
共 50 条
  • [41] The impact of COVID-19 on proctologic practice in Italy
    G. Gallo
    A. Sturiale
    V. De Simone
    G. L. Di Tanna
    F. Bianco
    R. Perinotti
    I. Giani
    U. Grossi
    Techniques in Coloproctology, 2020, 24 : 1103 - 1104
  • [42] The impact of COVID-19 on proctologic practice in Italy
    Gallo, G.
    Sturiale, A.
    De Simone, V.
    Di Tanna, G. L.
    Bianco, F.
    Perinotti, R.
    Giani, I.
    Grossi, U.
    TECHNIQUES IN COLOPROCTOLOGY, 2020, 24 (10) : 1103 - 1104
  • [43] Impact of tiered restrictions on human activities and the epidemiology of the second wave of COVID-19 in Italy
    Manica, Mattia
    Guzzetta, Giorgio
    Riccardo, Flavia
    Valenti, Antonio
    Poletti, Piero
    Marziano, Valentina
    Trentini, Filippo
    Andrianou, Xanthi
    Mateo-Urdiales, Alberto
    del Manso, Martina
    Fabiani, Massimo
    Vescio, Maria Fenicia
    Spuri, Matteo
    Petrone, Daniele
    Bella, Antonino
    Iavicoli, Sergio
    Ajelli, Marco
    Brusaferro, Silvio
    Pezzotti, Patrizio
    Merler, Stefano
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [44] Impact of tiered restrictions on human activities and the epidemiology of the second wave of COVID-19 in Italy
    Mattia Manica
    Giorgio Guzzetta
    Flavia Riccardo
    Antonio Valenti
    Piero Poletti
    Valentina Marziano
    Filippo Trentini
    Xanthi Andrianou
    Alberto Mateo-Urdiales
    Martina del Manso
    Massimo Fabiani
    Maria Fenicia Vescio
    Matteo Spuri
    Daniele Petrone
    Antonino Bella
    Sergio Iavicoli
    Marco Ajelli
    Silvio Brusaferro
    Patrizio Pezzotti
    Stefano Merler
    Nature Communications, 12
  • [45] Economic disturbances in the COVID-19 crisis and their gendered impact on unpaid activities in Germany and Italy
    Kulic, Nevena
    Dotti Sani, Giulia M.
    Strauss, Susanne
    Bellani, Luna
    EUROPEAN SOCIETIES, 2021, 23 : S400 - S416
  • [46] COVID-19: Impact on prescribing and antimicrobial resistance
    Ruiz-Garbajosa, Patricia
    Canton, Rafael
    REVISTA ESPANOLA DE QUIMIOTERAPIA, 2021, 34 : 63 - 68
  • [47] Impact of a region wide antimicrobial stewardship guideline on urinary tract infection prescription patterns
    Celine Slekovec
    Joël Leroy
    Nathalie Vernaz-Hegi
    Jean-Pierre Faller
    Danièle Sekri
    Bruno Hoen
    Daniel Talon
    Xavier Bertrand
    International Journal of Clinical Pharmacy, 2012, 34 : 325 - 329
  • [48] Impact of a region wide antimicrobial stewardship guideline on urinary tract infection prescription patterns
    Slekovec, Celine
    Leroy, Joel
    Vernaz-Hegi, Nathalie
    Faller, Jean-Pierre
    Sekri, Daniele
    Hoen, Bruno
    Talon, Daniel
    Bertrand, Xavier
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACY, 2012, 34 (02) : 325 - 329
  • [49] Covid-19 in Italy: Lesson from the Veneto Region
    Mugnai, Giacomo
    Bilato, Claudio
    EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2020, 77 : 161 - 162
  • [50] Collateral damage of the COVID-19 pandemic: Exacerbation of antimicrobial resistance and disruptions to antimicrobial stewardship programmes?
    Chibabhai, V.
    Duse, A. G.
    Perovic, O.
    Richards, G. A.
    SAMJ SOUTH AFRICAN MEDICAL JOURNAL, 2020, 110 (07): : 572 - 573