HMGB1 mediates invasion and PD-L1 expression through RAGE-PI3K/AKT signaling pathway in MDA-MB-231 breast cancer cells

被引：0
|
作者：
Kamolporn Amornsupak
Suyanee Thongchot
Chanida Thinyakul
Carol Box
Somaieh Hedayat
Peti Thuwajit
Suzanne A. Eccles
Chanitra Thuwajit
机构：
[1] Faculty of Allied Health Sciences,Department of Transfusion Medicine and Clinical Microbiology
[2] Chulalongkorn University,Department of Immunology, Faculty of Medicine Siriraj Hospital
[3] Immunomodulation of Natural Products Research Group,Siriraj Center of Research Excellence for Cancer Immunotherapy, Research Department
[4] Faculty of Allied Health Sciences,undefined
[5] Chulalongkorn University,undefined
[6] Mahidol University,undefined
[7] Faculty of Medicine Siriraj Hospital,undefined
[8] Mahidol University,undefined
[9] Centre For Cancer Imaging,undefined
[10] Division of Radiotherapy and Imaging,undefined
[11] The Institute of Cancer Research,undefined
[12] Present Address: Cancer Research UK,undefined
[13] Cancer Therapeutics Unit,undefined
[14] The Institute of Cancer Research,undefined
来源：
BMC Cancer | / 22卷
关键词：
Breast cancer; HMGB1; RAGE; PI3K-AKT; Migration; Invasion; PD-L1;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [11] The acidic tumor microenvironment enhances PD-L1 expression via activation of STAT3 in MDA-MB-231 breast cancer cells
    Yong-Jin Kwon
    Eun-Bi Seo
    Ae Jin Jeong
    Song-Hee Lee
    Kum Hee Noh
    Sangsik Lee
    Chung-Hyun Cho
    Chang-Han Lee
    Hyun Mu Shin
    Hang-Rae Kim
    Hyeong-Gon Moon
    Sang-Kyu Ye
    BMC Cancer, 22
  • [12] The acidic tumor microenvironment enhances PD-L1 expression via activation of STAT3 in MDA-MB-231 breast cancer cells
    Kwon, Yong-Jin
    Seo, Eun-Bi
    Jeong, Ae Jin
    Lee, Song-Hee
    Noh, Kum Hee
    Lee, Sangsik
    Cho, Chung-Hyun
    Lee, Chang-Han
    Shin, Hyun Mu
    Kim, Hang-Rae
    Moon, Hyeong-Gon
    Ye, Sang-Kyu
    BMC CANCER, 2022, 22 (01)
  • [13] Rhapontigenin Suppresses Cell Migration and Invasion by Inhibiting the PI3K-Dependent Rac1 Signaling Pathway in MDA-MB-231 Human Breast Cancer Cells
    Kim, Ji Sung
    Kang, Chi Gu
    Kim, Sung-Hoon
    Lee, Eun-Ok
    JOURNAL OF NATURAL PRODUCTS, 2014, 77 (05): : 1135 - 1139
  • [14] Moscatilin inhibits migration and metastasis of human breast cancer MDA-MB-231 cells through inhibition of Akt and Twist signaling pathway
    Hui-Chen Pai
    Li-Hsun Chang
    Chieh-Yu Peng
    Ya-Ling Chang
    Chien-Chih Chen
    Chien-Chang Shen
    Che-Ming Teng
    Shiow-Lin Pan
    Journal of Molecular Medicine, 2013, 91 : 347 - 356
  • [15] Docosahexaenoic acid inhibits the invasion of MDA-MB-231 breast cancer cells through upregulation of cytokeratin-1
    Blanckaert, Vincent
    Kerviel, Vincent
    Lepinay, Alexandra
    Joubert-Durigneux, Vanessa
    Hondermarck, Hubert
    Chenais, Benoit
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2015, 46 (06) : 2649 - 2655
  • [16] Circular RNA circASS1 is downregulated in breast cancer cells MDA-MB-231 and suppressed invasion and migration
    Hou, Jun-chen
    Xu, Zhi
    Zhong, Shan-liang
    Zhang, He-da
    Jiang, Lin-hong
    Chen, Xiu
    Zhu, Ling-ping
    Li, Jian
    Zhou, Si-ying
    Yang, Su-jin
    He, Yun-jie
    Wang, Dan-dan
    Deng, Fei
    Zhang, Qian
    Wang, Jin-yan
    Hu, Jia-hua
    Zhang, Wei
    Wu, Yang
    Ding, Li
    Zhao, Jian-hua
    Tang, Jin-hai
    EPIGENOMICS, 2019, 11 (02) : 199 - 213
  • [17] Carbonic anhydrase XII promotes invasion and migration ability of MDA-MB-231 breast cancer cells through the p38 MAPK signaling pathway
    Hsieh, Ming-Ju
    Chen, Kuo-Shuen
    Chiou, Hui-Ling
    Hsieh, Yih-Shou
    EUROPEAN JOURNAL OF CELL BIOLOGY, 2010, 89 (08) : 598 - 606
  • [18] Electrochemotherapy inhibited breast cancer MDA-MB231 cell migration and invasion through PI3K/AKT signal pathway
    Zhou, Bing-Gang
    Wei, Chang-Sheng
    Zhang, Song
    Zhang, Zhi
    Shen, Yi-Jun
    Wang, Jian
    Gao, Huan-Min
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2016, 9 (09): : 18513 - 18518
  • [19] Lucidone inhibits autophagy and MDR1 via HMGB1/RAGE/PI3K/Akt signaling pathway in pancreatic cancer cells
    Chen, Sheng-Yi
    Hsu, Yi-Hao
    Wang, Sheng-Yang
    Chen, Ying-Yin
    Hong, Cheng-Jie
    Yen, Gow-Chin
    PHYTOTHERAPY RESEARCH, 2022, 36 (04) : 1664 - 1677
  • [20] Tumor suppressive activity of miR-424-5p in breast cancer cells through targeting PD-L1 and modulating PTEN/PI3K/AKT/mTOR signaling pathway
    Dastmalchi, Narges
    Hosseinpourfeizi, Mohammad Ali
    Khojasteh, Seyed Mahdi Banan
    Baradaran, Behzad
    Safaralizadeh, Reza
    LIFE SCIENCES, 2020, 259
12345