Maternal smoking during pregnancy and risk of cryptorchidism: a systematic review and meta-analysis

被引:0
作者
Chengjun Yu
Yi Wei
Xiangliang Tang
Bin Liu
Lianju Shen
Chunlan Long
Tao Lin
Dawei He
Shengde Wu
Guanghui Wei
机构
[1] Children’s Hospital of Chongqing Medical University,Department of Urology
[2] Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering,undefined
[3] Ministry of Education Key Laboratory of Child Development and Disorders,undefined
[4] China International Science and Technology Cooperation Base of Child Development and Critical Disorders,undefined
[5] Chongqing Key Laboratory of Pediatrics Chongqing,undefined
来源
European Journal of Pediatrics | 2019年 / 178卷
关键词
Cryptorchidism; Maternal smoking; Meta-analysis;
D O I
暂无
中图分类号
学科分类号
摘要
The risk factors for undescended testes in male infants and the underlying pathogenesis still remain unclear. The aim of this study is to identify the relationship between maternal smoking during pregnancy and risk of cryptorchidism. A systematic review was conducted using appropriate search terms to identify articles pertaining to maternal smoking during pregnancy and risk of cryptorchidism. Entries up to December 23, 2017 were taken into consideration, without any language or regional restriction. The crude ORs and their 95% CIs were computed by using the fixed-effect model. Twenty studies involving 111,712 infants were included in our meta-analysis. The risk of having a male infant with cryptorchidism was significantly different between mothers who smoked during pregnancy and those who did not (pooled crude OR 1.18, 95% confidence interval [CI] 1.12–1.24, p < 0.00001).
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页码:287 / 297
页数:10
相关论文
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