VildagliptinA Review of its Use in Type 2 Diabetes Mellitus

被引：0
作者：
Gillian M. Keating
机构：
[1] Adis,
[2] a Wolters Kluwer Business,undefined
来源：
Drugs | 2010年 / 70卷
关键词：
Metformin; Rosiglitazone; Pioglitazone; Acarbose; Sitagliptin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Vildagliptin (Galvus®, Jalra®, Xiliarx®) is an orally administered dipeptidyl peptidase-4 (DPP-4) inhibitor. In patients with type 2 diabetes mellitus, vildagliptin 50mg twice daily is indicated for use in combination with metformin or a thiazolidinedione, and vildagliptin 50mg once daily is indicated for use in combination with a sulfonylurea. A fixed-dose combination of vildagliptin/metformin (Eucreas®, Icandra®, Zomarist®) is also available. This article reviews the clinical efficacy and tolerability of vildagliptin in patients with type 2 diabetes, as well as summarizing its pharmacological properties.
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页码：2089 / 2112
页数：23
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