Fatal thrombotic thrombocytopenic purpura as a rare complication following allogeneic stem cell transplantation

被引：0

作者：

J. Chemnitz

M. Fuchs

W. Blau

P. Hartmann

C. Wickenhauser

C. Scheid

A. Schulz

V. Diehl

D. Söhngen

机构：

[1] I. Department of Medicine,

[2] University of Cologne,undefined

[3] Joseph-Stelzmann-Str. 9,undefined

[4] D-50924 Köln,undefined

[5] Germany e-mail: jens.chemnitz@uni-koeln.de Tel.: +49-221-4785044 Fax: +49-221-4786417,undefined

[6] Department of Bone Marrow Transplantation and Hematology,undefined

[7] Dr. Ottmar-Kohler-Str. 2,undefined

[8] D-55743 Idar-Oberstein,undefined

[9] Germany,undefined

[10] Department of Pathology,undefined

[11] University of Cologne,undefined

[12] Joseph-Stelzmann-Str. 9,undefined

[13] D-50924 Köln,undefined

[14] Germany,undefined

来源：

Annals of Hematology | 2000年 / 79卷

关键词：

Key words Stem cell transplantation; Thrombotic thrombocytopenic purpura; Plasmapheresis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Thrombotic thrombocytopenic purpura (TTP) is a rare disease which, together with hemolytic uremic syndrome, is subsumed under thrombotic microangiopathy. After stem cell transplantation (SCT), this syndrome represents a possibly fatal complication with a higher incidence in allogeneic SCT than in autologous SCT. Although plasmapheresis offers an encouraging treatment modality in classic TTP, this seems less effective in bone marrow transplant-associated microangiopathy. This is probably due to a different etiology. We present a case of transplant-associated TTP with a fatal outcome despite multiple courses of plasmapheresis.

引用

页码：527 / 529

页数：2