Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity

被引：0
|
作者：
Collin J Kreple
Yuan Lu
Rebecca J Taugher
Andrea L Schwager-Gutman
Jianyang Du
Madeliene Stump
Yimo Wang
Ali Ghobbeh
Rong Fan
Caitlin V Cosme
Levi P Sowers
Michael J Welsh
Jason J Radley
Ryan T LaLumiere
John A Wemmie
机构：
[1] Medical Scientist Training Program,Department of Molecular Physiology and Biophysics
[2] University of Iowa,Department of Psychiatry
[3] University of Iowa,Department of Psychology
[4] University of Iowa,Department of Internal Medicine
[5] Interdisciplinary Graduate Program in Neuroscience,Department of Neurology
[6] University of Iowa,Department of Neurosurgery
[7] University of Iowa,undefined
[8] University of Iowa,undefined
[9] University of Iowa,undefined
[10] University of Iowa,undefined
[11] Howard Hughes Medical Institute,undefined
[12] Department of Veterans Affairs Medical Center,undefined
来源：
Nature Neuroscience | 2014年 / 17卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Exposure to psychostimulants such as cocaine induces synaptic plasticity within the nucleus accumbens (NAc) and alters behavior. Here the authors find a new role for the acid-sensing channel 1A (ASIC1A) in excitatory transmission and plasticity within the NAc that contributes to cocaine-induced learning and self-administration.
引用
收藏
页码：1083 / 1091
页数：8
相关论文
共 50 条
  • [31] RETRACTED: Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration (Retracted Article)
    Behan, A. T.
    Breen, B.
    Hogg, M.
    Woods, I.
    Coughlan, K.
    Mitchem, M.
    Prehn, J. H. M.
    CELL DEATH AND DIFFERENTIATION, 2013, 20 (04): : 589 - 598
  • [32] Comment on "Acid-Sensing Ion Channels Contribute to the Effect of Acidosis on the Function of Dendritic Cells"
    Li, Xia
    Yuan, Feng-Lai
    Zhao, Qing-Yi
    Lu, Wei-Guo
    Li, Jian-Ping
    Li, Cheng-Wan
    JOURNAL OF IMMUNOLOGY, 2011, 186 (12): : 6647 - 6647
  • [33] Acid-Sensing Ion Channels in Pathological Conditions
    Chu, Xiang-Ping
    Xiong, Zhi-Gang
    SODIUM CALCIUM EXCHANGE: A GROWING SPECTRUM OF PATHOPHYSIOLOGICAL IMPLICATIONS, 2013, 961 : 419 - 431
  • [34] Acid-sensing ion channels in allergic rhinitis
    KleinJan, A.
    CLINICAL AND EXPERIMENTAL ALLERGY, 2012, 42 (07): : 988 - 990
  • [35] Acid-sensing ion channels under hypoxia
    Guo Yingjun
    Qu Xun
    CHANNELS, 2013, 7 (04) : 231 - 237
  • [36] Acid-sensing ion channels in gastrointestinal function
    Holzer, Peter
    NEUROPHARMACOLOGY, 2015, 94 : 72 - 79
  • [37] Acid-sensing ion channels in malignant gliomas
    Berdiev, BK
    Xia, JZ
    McLean, LA
    Markert, JM
    Gillespie, GY
    Mapstone, TB
    Naren, AP
    Jovov, B
    Bubien, JK
    Ji, HL
    Fuller, CM
    Kirk, KL
    Benos, DJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (17) : 15023 - 15034
  • [38] Role of acid-sensing ion channels in glaucoma
    Saugstad, J
    Dong, J
    Chu, XP
    Xiong, ZG
    Simon, RP
    Engelman, CJ
    Cioffi, GA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 : U773 - U773
  • [39] Peptide Modulation of Acid-Sensing Ion Channels
    Borg, Christian B.
    Haugaard-Kedstrom, Linda M.
    Lynagh, Timothy
    Stromgaard, Kristian
    Pless, Stephan A.
    BIOPHYSICAL JOURNAL, 2018, 114 (03) : 130A - 130A
  • [40] The functions of acid-sensing ion channels and their modulations
    Wu, LJ
    Xu, TL
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2003, 30 (03) : 339 - 343
12345