A Giant Cystic Pheochromocytoma of the Adrenal Gland

被引:0
作者
Zenggang Pan
Susan Repertinger
Caishu Deng
Poonam Sharma
机构
[1] Creighton University Medical Center,Department of Pathology
来源
Endocrine Pathology | 2008年 / 19卷
关键词
pheochromocytoma; giant; adrenal gland;
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学科分类号
摘要
Adrenal pheochromocytomas are rare catecholamine-secreting tumors that originate from chromaffin cells in the adrenal medulla, and giant pheochromocytomas with cystic changes are particularly rare. We report a case of a 46-year-old man who presented with episodic hypertension and headache. Radiographic studies showed an 18-cm cystic mass in the left upper quadrant of the abdomen; further workups, which included light microscopy, immunohistochemical, and electron microscopic analysis, revealed a pheochromocytoma of the left adrenal gland. Cytogenetic analysis and genetic mutation analyses for von-Hippel–Lindau (VHL), rearranged during transfection (RET), and succinate dehydrogenase complex subunit B (SDHB) genes were also performed but failed to reveal any abnormalities within the tumor cells.
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页码:133 / 138
页数:5
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