Radiation-induced esophageal strictures in children with cancer

被引:0
|
作者
S. Mahboubi
J. H. Silber
机构
[1] Department of Radiology,
[2] Division of Oncology,undefined
[3] The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine,undefined
[4] Philadelphia,undefined
[5] Pennsylvania 19104,undefined
[6] USA,undefined
[7] Department of Pediatrics,undefined
[8] Division of Oncology,undefined
[9] The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine,undefined
[10] Philadelphia,undefined
[11] Pennsylvania 19104,undefined
[12] USA,undefined
来源
European Radiology | 1997年 / 7卷
关键词
Key words: Pediatric; Esophageal stricture; Radiation esophagitis; Mediastinal irradiation; Cancer; Long-term follow-up; Late effects; Chemotherapy;
D O I
暂无
中图分类号
学科分类号
摘要
The purpose of this study was to determine the long-term esophageal side effects of irradiation and (doxorubicin) chemotherapy given to children with cancer. Barium esophagograms and medical records of 18 patients with esophagitis who received between 1200 and 5580 cGy to the chest and chemotherapy were reviewed. The age range was 3–14 years. Esophageal strictures occuring 1–10 years after therapy were found in 5 patients with lymphoma; 3 of the five received doses of 4000 cGy or greater. Three children with esophagitis who received doses of 4000 cGy did not have stricture formation. However, their follow-up time was only 1–3 years. Of the 5 patients with esophageal stricture, 4 were treated with multiple dilatations, and a fifth required colonic interposition. Combined mediastinal irradiation and chemotherapy can result in esophageal stricture 1–10 years after therapy.
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页码:119 / 122
页数:3
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