Bacterial clearance in Crohn's disease pathogenesis

被引：0
作者：
Francesca Fava
Silvio Danese
机构：
[1] IBD Unit,Division of Gastroenterology
[2] Istituto Clinico Humanitas IRCCS,undefined
来源：
Nature Reviews Gastroenterology & Hepatology | 2010年 / 7卷
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摘要：
Evidence from a recent study strongly implicates innate immunity in the etiology of Crohn's disease, with particular focus on impaired secretion of cytokines and chemokines by intestinal macrophages in response to bacterial stimuli. These findings highlight the importance of acute inflammatory responses in the first stages of disease pathogenesis.
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页码：126 / 128
页数：2
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