SLE and pregnancy: the potential role for regulatory T cells

被引：0
作者：
Clare Tower
Ian Crocker
Debora Chirico
Philip Baker
Ian Bruce
机构：
[1] Maternal and Fetal Health Research Center,
[2] Arthritis Research UK Epidemiology Unit,undefined
[3] Manchester Academic Health Sciences Center,undefined
[4] The University of Manchester,undefined
来源：
Nature Reviews Rheumatology | 2011年 / 7卷
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摘要：
Pregnancy in women with systemic lupus erythematosus (SLE) can be associated with substantial morbidity and mortality for both the mother and the unborn fetus. Findings from several studies have indicated that CD4+CD25+regulatory T cells have an important role in supporting a healthy pregnancy. In this article, the authors provide an overview of how regulatory T cells function in both SLE and pregnancy, as well as providing an insight into how therapeutic agents that induce these cells could promote successful pregnancy in women with SLE.
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页码：124 / 128
页数：4
相关论文
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