Blood-Brain Barrier Transport of Reduced Folic Acid

被引：0
作者：
Dafang Wu
William M. Pardridge
机构：
[1] UCLA School of Medicine,Department of Medicine
来源：
Pharmaceutical Research | 1999年 / 16卷
关键词：
folate receptor; folic acid; blood-brain barrier; drug delivery;
D O I：
暂无
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学科分类号：
摘要：
Purpose. The brain is relatively resistant to folic acid deficiency, indicating specialized transport systems may exist for this vitamin localized within the brain capillary endothelial wall, which makes up the blood-brain barrier (BBB) in vivo. The present studies quantify the BBB transport of [3H]-methyltetrahydrofolic acid (MTFA) in vivo and in isolated human brain capillaries in vitro.
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页码：415 / 419
页数：4
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