Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells

[1] Huwiler A(2000)Physiology and pathophysiology of sphingolipid metabolism and signaling Biochim Biophys Acta 1485 63-99

[2] Kolter T(2002)Ganglioside G(M3) overexpression induces apoptosis and reduces malignant potential in murine bladder cancer Cancer Res 62 3850-3854

[3] Pfeilschifter J(2005)Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells Proc Natl Acad Sci USA 102 11041-11046

[4] Sandhoff K(2001)Glycolipid composition in bladder tumor: a crucial role of GM3 ganglioside in tumor invasion Int J Cancer 94 343-347

[5] Watanabe R(2006)Sphingolipids in tumor metastases and angiogenesis Biochemistry (Mosc) 71 347-353

[6] Ohyama C(1999)Lipid characteristics in metastatic cells Clin Exp Metastasis 17 271-276

[7] Aoki H(1987)Glycosphingolipids of lectin-resistant mutants of the highly metastatic mouse tumor cell line, MDAY-D2 Cancer Res 47 150-159

[8] Takahashi T(2003)Correlation of gangliosides GM2 and GM3 with metastatic potential to lungs of mouse B16 melanoma J Exp Clin Cancer Res 22 125-134

[9] Satoh M(1979)Ganglioside patterns of metastatic and non-metastatic transplantable hepatocellular carcinomas of the rat J Supramol Struct 11 485-492

[10] Saito S(2001)Enhanced GM3 expression, associated with decreased invasiveness, is induced by brefeldin A in bladder cancer cells Int J Oncol 19 723-731

[1] Huwiler A(2000)Physiology and pathophysiology of sphingolipid metabolism and signaling Biochim Biophys Acta 1485 63-99

[2] Kolter T(2002)Ganglioside G(M3) overexpression induces apoptosis and reduces malignant potential in murine bladder cancer Cancer Res 62 3850-3854

[3] Pfeilschifter J(2005)Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells Proc Natl Acad Sci USA 102 11041-11046

[4] Sandhoff K(2001)Glycolipid composition in bladder tumor: a crucial role of GM3 ganglioside in tumor invasion Int J Cancer 94 343-347

[5] Watanabe R(2006)Sphingolipids in tumor metastases and angiogenesis Biochemistry (Mosc) 71 347-353

[6] Ohyama C(1999)Lipid characteristics in metastatic cells Clin Exp Metastasis 17 271-276

[7] Aoki H(1987)Glycosphingolipids of lectin-resistant mutants of the highly metastatic mouse tumor cell line, MDAY-D2 Cancer Res 47 150-159

[8] Takahashi T(2003)Correlation of gangliosides GM2 and GM3 with metastatic potential to lungs of mouse B16 melanoma J Exp Clin Cancer Res 22 125-134

[9] Satoh M(1979)Ganglioside patterns of metastatic and non-metastatic transplantable hepatocellular carcinomas of the rat J Supramol Struct 11 485-492

[10] Saito S(2001)Enhanced GM3 expression, associated with decreased invasiveness, is induced by brefeldin A in bladder cancer cells Int J Oncol 19 723-731