Functional heartburn: misdiagnosed gastroesophageal reflux or a distinct entity?

被引:0
作者
Ronnie Fass
Ram Dickman
机构
[1] Head,
[2] Neuro-Enteric Clinical Research Group at Southern Arizona VA Health Care System,undefined
[3] research fellow of the Neuro-Enteric Clinical Research Group at Southern Arizona VA Health Care System,undefined
来源
Nature Clinical Practice Gastroenterology & Hepatology | 2005年 / 2卷
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摘要
For many years functional heartburn has been linked to gastroesophageal reflux disease, despite a number of characteristics that set this disorder apart. As such little has been researched regarding the physiology and treatment of patients with functional heartburn as a distinct entity. This Viewpoint discusses the evidence for distinguishing this group of patients.
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页码:120 / 121
页数:1
相关论文
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  • [1] Fass R(2001)Nonerosive reflux disease—current concepts and dilemmas Am J Gastroenterol 96 303-314
  • [2] Fass R(1998)Differential effect of long-term esophageal acid exposure on mechanosensitivity and chemosensitivity in humans Gastroenterology 115 1363-1373
  • [3] Lind T(1997)Heartburn without oesophagitis: efficacy of omeprazole therapy and features determining therapeutic response Scand J Gastroenterol 32 974-979
  • [4] Richter JE(2000)Lansoprazole compared with ranitidine for the treatment of nonerosive gastroesophageal reflux disease Arch Intern Med 160 1803-1809
  • [5] Fass R(2000)Omeprazole 40 mg once a day is equally effective as lansoprazole 30 mg twice a day in symptom control of patients with gastro-oesophageal reflux disease (GERD) who are resistant to conventional-dose lansoprazole therapy—a prospective, randomized, multi-centre study Aliment Pharmacol Ther 14 1595-1603
  • [6] Frazzoni M(2004)Pathophysiological characteristics of patients with non-erosive reflux disease differ from those of patients with functional heartburn Aliment Pharmacol Ther 20 81-88
  • [7] Martinez SD(2003)Non-erosive reflux disease (NERD)—acid reflux and symptom patterns Aliment Pharmacol Ther 17 537-545
  • [8] Watson RG(1997)Double blind cross-over placebo controlled study of omeprazole in the treatment of patients with reflux symptoms and physiological levels of acid reflux—the “sensitive oesophagus” Gut 40 587-590
  • [9] Fass R(2002)Functional heartburn: the stimulus, the pain, and the brain Gut 51 885-892
  • [10] Tougas G(2004)The role of esophageal afferent pathway sensitivity in non-erosive reflux disease [abstract #128] Gastroenterology 126 A-18-undefined