4-Hydroxy-2-quinolones 126. 1-Hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1- ij]quinoline-2-carboxylic acid hydrazide and its derivatives

被引：0

作者：

Ukrainets I.V. ^{[1
]}

Tkach A.A. ^{[2
]}

Mospanova E.V. ^{[2
]}

Svechnikova E.N. ^{[2
]}

机构：

[1] National University of Pharmacy

来源：

Chemistry of Heterocyclic Compounds | 2007年 / 43卷 / 08期

关键词：

4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acids; Amidation; Antitubercular activity; Hydrazinolysis;

D O I：

10.1007/s10593-007-0158-y

中图分类号：

学科分类号：

摘要：

A preparative method has been developed for the synthesis of 1-hydroxy-3-oxo-5,6-dihydro-3H pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid hydrazide and its derivatives. The results of a study of the antitubercular activity of the synthesized compounds are presented. © 2007 Springer Science+Business Media, Inc.

引用

页码：1014 / 1019

页数：5

共 20 条

[11] Chem. Heterocycl. Comp., 30, (1994)
[12] Heifets L.B., Heifets L.B., Drug Susceptibility in the Chemistry of Mycobacterial Infections, (1991)
[13] Inderleid C.B., Nash K.A., Lorian V., Antibiotics in Laboratory Medicine, (1996)
[14] Albert A., Sergeant E.P., Ionization Constants of Acids and Bases, (1964)
[15] L'Vovskii E.N., Statistical Methods for Deriving Empirical Formulae, (1988)
[16] Ukrainets I.V., Sidorenko L.V., Gorokhova O.V., Mospanova E.V., Shishkin O.V., Khim. Geterotsikl. Soedin., (2006)
[17] Chem. Heterocycl. Comp., 42, (2006)
[18] Jonsson S., Andersson G., Fex T., Fristedt T., Hedlund G., Jansson K., Abramo L., Fritzson I., Pekarski O., Runstrom A., Sandin H., Thuvesson I., Bjork A., J. Med. Chem., 47, (2004)
[19] Ukrainets I.V., Gorokhova O.V., Taran S.G., Bezugly P.A., Turov A.V., Marusenko N.A., Evtifeeva O.A., Khim. Geterotsikl. Soedin., (1994)
[20] Chem. Heterocycl. Comp., 30, (1994)

← 1 2 →