Incidence of respiratory viruses in patients with community-acquired pneumonia admitted to the intensive care unit: results from the Severe Influenza Pneumonia Surveillance (SIPS) project

被引：0
作者：
T. Wiemken
P. Peyrani
K. Bryant
R. R. Kelley
J. Summersgill
F. Arnold
R. Carrico
W. P. McKinney
C. Jonsson
K. Carrico
J. Ramirez
机构：
[1] University of Louisville,Division of Infectious Diseases
[2] Kosair Children’s Hospital,Division of Pediatric Infectious Diseases
[3] University of Louisville,Department of Health Promotion and Behavioral Sciences, School of Public Health and Information Sciences
[4] University of Louisville,Center for Health Hazards Preparedness, School of Public Health and Information Sciences
[5] University of Louisville,Center for Predictive Medicine, Department of Microbiology and Immunology
[6] University of Louisville,Division of Infectious Diseases, Clinical and Translational Research Support Center
来源：
European Journal of Clinical Microbiology & Infectious Diseases | 2013年 / 32卷
关键词：
Influenza; Influenza Virus; Etiologic Agent; Multiplex Polymerase Chain Reaction; Respiratory Virus;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Few patients with community-acquired pneumonia (CAP) require admission to the intensive care unit (ICU-CAP). However, they represent the most severe form of the disease. An understanding of the etiologic agents of ICU-CAP may lead to better treatment decisions and patient outcomes. The objective of this study was to determine the incidence of respiratory viruses in patients with ICU-CAP. This was an observational study conducted in six Kentucky hospitals from December 2008 through October 2011. A case of ICU-CAP was defined as a patient admitted to an ICU with the diagnosis of CAP. The Luminex xTAG multiplex polymerase chain reaction (PCR) assay was used for viral identification. A total of 468 adult and pediatric patients with ICU-CAP were enrolled in the study. A total of 92 adult patients (23 %) and 14 pediatric patients (19 %) had a respiratory virus identified. Influenza was the most common virus identified in adults and the second most common in pediatric patients. This study suggests that respiratory viruses may be common etiologic agents of pneumonia in patients with ICU-CAP. The Centers for Disease Control and Prevention (CDC) recommend empiric anti-influenza therapy during the winter for hospitalized patients with CAP. This study supports this recommendation in patients with ICU-CAP.
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页码：705 / 710
页数：5
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