The density, viscosity and structural properties of aqueous ethambutol hydrochloride solutions

被引：0
作者：
S. D. Deosarkar
A. L. Puyad
T. M. Kalyankar
机构：
[1] Swami Ramanand Teerth Marathwada University,School of Chemical Sciences
[2] Swami Ramanand Teerth Marathwada University,India School of Pharmacy
来源：
Russian Journal of Physical Chemistry A | 2012年 / 86卷
关键词：
aqueous ethambutol hydrochloride solutions; density; viscosity and structural properties;
D O I：
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中图分类号：
学科分类号：
摘要：
Ethambutol (EMB) is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is bacteriostatic against actively growing TB bacilli. The density and viscosity of aqueous ethambutol hydrochloride solutions have been studied at 298.15, 301.15 and 304.15 K and at different concentrations (0.255, 0.168, 0.128, 0.087, 0.041, and 0.023 mol dm−3). The apparent molar volume of these solutions for different temperatures and concentrations was calculated from the density data. The relative viscosities of drug solutions have been analysed by Jones-Dole equation. The limiting apparent molar volumes have been evaluated for different temperatures. The different properties have been used to study structural properties, structure formation and breaking properties of drug and solute-solvent interactions in solutions.
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页码：775 / 778
页数：3
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