P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice

被引:0
作者
Zhi Ruan
Jean-Christophe Delpech
Srinidhi Venkatesan Kalavai
Alicia A. Van Enoo
Jianqiao Hu
Seiko Ikezu
Tsuneya Ikezu
机构
[1] Boston University School of Medicine,Department of Pharmacology & Experimental Therapeutics
[2] Boston University School of Medicine,Alzheimer’s Disease Center
[3] Boston University,Center for Systems Neuroscience
[4] Boston University School of Medicine,Neurology
来源
Molecular Neurodegeneration | / 15卷
关键词
Alzheimer’s disease; Exosome; Extracellular vesicles; Microglia; Microtubule-associated protein tau; P2X purinoceptor 7; Tauopathy;
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