Synthetic biology with nanomaterials

被引：0
作者：
Sanhita Ray
Ahana Mukherjee
Pritha Chatterjee
Kaushik Chakraborty
Anjan Kr Dasgupta
机构：
[1] University of Calcutta,Department of Biochemistry
[2] University of California at Riverside,Department of Biochemistry and Molecular Biology
[3] Centre for Research in Nanoscience and Nanotechnology,undefined
[4] JD 2,undefined
来源：
MRS Communications | 2018年 / 8卷
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摘要：
Magnetic field has been used to trigger biofilm formation. Iron oxide nanoparticles were attached to bacterial cells and cells were aggregated by application of magnetic field. Artificial cellular crowding triggered quorum sensing and led to the formation of biofilm at the sub-threshold population. Aggregation process was monitored by studying temporal dynamics of capacitance and conductance profiles. Capacitive profile exhibited a plateau upon introduction of magnetic field which was retained even after field was removed. This hysteresis property signified biofilm initiation in response to artificial crowding. This work demonstrates how synthetic biology is enabled by including nanoparticles in the interactome.
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页码：100 / 106
页数：6
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  • [1] Jewett MC(2008)An integrated cell-free metabolic platform for protein production and synthetic biology Mol. Syst. Biol. 4 220-817
  • [2] Calhoun KA(2013)Quorum-sensing regulation of a capsular polysaccharide receptor for the Rhodobacter capsulatus gene transfer agent (rcgta) Mol. Microbiol. 87 802-33
  • [3] Voloshin A(2005)Sociomicrobiology: the connections between quorum sensing and biofilms. Trends Microbiol. 13 27-656
  • [4] Wuu JJ(2003)Quorum sensing-dependent biofilms enhance colonization in vibrio cholera. Dev. Cell 5 647-79
  • [5] Swartz JR(2000)Biofilm formation as microbial development. Annu. Rev. Microbiol. 54 49-327
  • [6] Brimacombe CA(2010)Bacterium in a box: sensing of quorum and environment by the luxi/luxr gene regulatory circuit. J. Biol. Phys. 36 317-132
  • [7] Stevens A(2014)Iron oxide nanoparticles induce Pseudomonas aeruginosa growth, induce biofilm formation, and inhibit antimicrobial peptide function Environ. Sci. Nano 1 123-170
  • [8] Jun D(2012)Spions increase biofilm formation by Pseudomonas aeruginosa. J. Biomater. Nanobiotechnol. 3 508-4005
  • [9] Mercer R(2015)Synthesis, characterization and theranostic evaluation of indium-111 labelled multifunctional superparamagnetic iron oxide nanoparticles. Nucl. Med. Biol. 42 164-278
  • [10] Lang AS(2012)Size-controlled synthesis of superparamagnetic iron oxide nanoparticles and their surface coating by gold for biomedical applications. J. Magn. Magn. Mater. 324 3997-5096
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