Epidemiology of multiple sclerosis in the pediatric population of Sardinia, Italy

被引：0
作者：
Silvia Dell’Avvento
Maria Alessandra Sotgiu
Salvatorica Manca
Giovanni Sotgiu
Stefano Sotgiu
机构：
[1] University of Sassari,Department of Clinical and Experimental Medicine, Section of Child Neuropsychiatry
[2] University of Sassari,Department of Biomedical Sciences, Human Anatomy
[3] Unit of Neuropsychiatry for Infants and Adolescents (UONPIA),Department of Biomedical Sciences, Clinical Epidemiology and Medical Statistics Unit
[4] ASL 1,undefined
[5] University of Sassari,undefined
[6] Research,undefined
[7] Medical Education and Professional Development Unit,undefined
[8] AOU Sassari,undefined
来源：
European Journal of Pediatrics | 2016年 / 175卷
关键词：
Multiple sclerosis; Clinically isolated syndrome; Children; Sardinia; Incidence; Prevalence;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). Several authors report MS affecting not only young adults but also children and adolescents. Sardinia is one of the regions at the highest risk for MS worldwide in the adult population; to date, no definite data exist on the pediatric population. The aim of this study was to estimate the incidence and prevalence of pediatric MS (pMS) in northern Sardinia. Patients with diagnosis of optic neuritis, myelitis, acute disseminated encephalomyelitis (ADEM), demyelinating disorders, MS, or clinically isolated syndrome (CIS) according to McDonald criteria were enrolled, when disease onset occurred within the range of 0–18 years. From January 1, 2001 to December 31, 2012, 21 cases of pMS and 5 cases of CIS were found in northern Sardinia. The annual mean pMS incidence was 2.85 cases per 100,000 pediatric population, and the annual mean CIS incidence was 0.68 cases per 100,000 pediatric population. The pMS and CIS prevalence computed on 31 December 2012 was 26.92 and 6.41 per 100,000 pediatric population, respectively.
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页码：19 / 29
页数：10
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