An Infant with Respiratory Distress and Loose Stools

被引：0
作者：
Poojitha Reddy
Devika Laishram
Ankur Kumar Jindal
Kirti Gupta
Amit Rawat
机构：
[1] Post Graduate Institute of Medical Education and Research,Department of Pathology
[2] Post Graduate Institute of Medical Education and Research,Allergy Immunology Unit, Department of Pediatrics
[3] Post Graduate Institute of Medical Education and Research,Department of Histopathology
来源：
Indian Pediatrics | 2018年 / 55卷
关键词：
Alopecia; Cytomegalovirus; Diarrhea; Lymphopenia; Pneumonia; Severe combined immunodeficiency;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We present the case of a 3-month-old girl who was admitted with complaints of loose stools and respiratory distress. She also had a history of rash and alopecia. Laboratory investigations revealed lymphopenia with reduced immunoglobulin G and immunoglobulin A. Lymphocyte subset analysis by flow cytometry revealed T-B+NK+ severe combined immunodeficiency (SCID). She died due to severe pneumonia, shock and pulmonary hemorrhage. Autopsy findings revealed disseminated cytomegalovirus infection in the lung, liver, adrenals and heart. Thymus was found to be dysplastic and showed characteristic histopathologic features of SCID.
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页码：693 / 697
页数：4
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