A randomized, double-blinded, placebo-controlled clinical trial of sterile filtered human amniotic fluid for treatment of COVID-19

被引：0

作者：

Joseph E. Tonna

Jan Pierce

Benjamin J. Brintz

Tyler Bardsley

Nathan Hatton

Giavonni Lewis

John D. Phillips

Chloe R. Skidmore

Craig H. Selzman

机构：

[1] Division of Cardiothoracic Surgery,Department of Surgery

[2] University of Utah Health,Department of Emergency Medicine

[3] University of Utah Health,Department of Medicine

[4] Division of Hematology,Department of Medicine

[5] Cell Therapy and Regenerative Medicine,Department of Medicine

[6] University of Utah School of Medicine,Department of Medicine

[7] Division of Epidemiology,Department of Surgery

[8] University of Utah School of Medicine,Department of Medicine

[9] Division of Epidemiology,Department of Surgery

[10] University of Utah School of Medicine,Department of Surgery

[11] Division of Pulmonary Medicine,undefined

[12] University of Utah Health,undefined

[13] Division of General Surgery,undefined

[14] University of Utah Health,undefined

[15] Division of Hematology,undefined

[16] Cell Therapy and Regenerative Medicine,undefined

[17] University of Utah School of Medicine,undefined

[18] Division of Cardiothoracic Surgery,undefined

[19] University of Utah Health,undefined

[20] Division of Cardiothoracic Surgery,undefined

[21] University of Utah Health,undefined

来源：

BMC Infectious Diseases | / 23卷

关键词：

Human amniotic fluid; COVID-19; Coronavirus; SARS-CoV2; Inflammation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 53 条

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[3] Benedetti E(2005)Amniotic fluid: not just fetal urine anymore J Perinatol 25 341-348
[4] Siggers J(1994)The immunomodulatory activity of human amniotic fluid can be correlated with transforming growth factor-beta 1 (TGF-beta 1) and beta 2 activity Clin Exp Immunol 97 158-163
[5] Ostergaard MV(2019)Processed human amniotic fluid retains its antibacterial activity J Transl Med 17 68-577
[6] Siggers RH(1989)Effect of amniotic fluid on bacterial recovery and growth: clinical implications Obstet Gynecol Surv 44 571-101
[7] Underwood MA(1986)Antimicrobial properties of amniotic fluid from some Nigerian women Int J Gynaecol Obstet 24 97-353
[8] Gilbert WM(2012)Influence of maternal age, gestational age and fetal gender on expression of immune mediators in amniotic fluid BMC Res Notes 5 375-507
[9] Sherman MP(2013)Effect of fresh human amniotic membrane dressing on graft take in patients with chronic burn wounds compared with conventional methods Burns 39 349-979
[10] Lang AK(2017)Anti-inflammatory properties of amniotic membrane patch following pericardiectomy for constrictive pericarditis J Cardiothorac Surg 12 6-377