The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells

被引:0
作者
Min Zhou
Joelle C. Boulos
Sabine M. Klauck
Thomas Efferth
机构
[1] Johannes Gutenberg University-Mainz,Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences
[2] National Center for Tumor Disease (NCT),Division of Cancer Genome Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK)
来源
Cell Biology and Toxicology | 2023年 / 39卷
关键词
Cardiac glycosides; Leukemia; MEK inhibitors; Parthanatos; Synthetic derivative; Transcriptomics;
D O I
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中图分类号
学科分类号
摘要
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页码:2971 / 2997
页数:26
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