Study of Antiparkinsonic Activity of Panavir on a Model of Parkinson Syndrome Induced by Systemic Administration of MPTP to Outbred Rats and C57Bl/6 Mice

被引:0
作者
T. S. Kalinina
L. N. Nerobkova
T. A. Voronina
S. V. Stovbun
A. A. Litvin
V. I. Sergienko
机构
[1] Russian Academy of Medical Sciences,V. V. Zakusov Institute of Pharmacology
[2] Ministry of Health of the Russian Federation,Institute of Physicochemical Medicine
来源
Bulletin of Experimental Biology and Medicine | 2005年 / 140卷
关键词
Parkinson's syndrome; MPTP; neurotoxin; dopamine;
D O I
暂无
中图分类号
学科分类号
摘要
The effect of panavir on Parkinson's syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine was studied in C57Bl/6 mice and outbred albino rats. Two injections of panavir significantly reduced the severity of oligokinesia and autonomic manifestations of experimentally induced Parkinson's syndrome.
引用
收藏
页码:55 / 57
页数:2
相关论文
共 13 条
  • [1] Val'dman E. A.(2001)undefined Ibid. 2 71-74
  • [2] Nezhinskaya G. I.(1989)undefined Byull. Eksp. Biol. Med. 107 147-150
  • [3] Nazarov P. G.(1993)undefined Zh. Nevropatol. Psikhiatr. 93 3-7
  • [4] Voronina T. A.(2000)undefined Byull. Eksp. Biol. Med. 130 20-23
  • [5] Kryzhanovskii G. N.(undefined)undefined undefined undefined undefined-undefined
  • [6] Atadzhanov M. A.(undefined)undefined undefined undefined undefined-undefined
  • [7] Voronina T. A.(undefined)undefined undefined undefined undefined-undefined
  • [8] Kryzhanovskii G. N.(undefined)undefined undefined undefined undefined-undefined
  • [9] Atadzhanov M. A.(undefined)undefined undefined undefined undefined-undefined
  • [10] Voronina T. A.(undefined)undefined undefined undefined undefined-undefined