Comparison of the impact of Tripterygium wilfordii Hook F and Methotrexate treatment on radiological progression in active rheumatoid arthritis: 2-year follow up of a randomized, non-blinded, controlled study

被引：0
作者：
Yang-zhong Zhou
Li-dan Zhao
Hua Chen
Yan Zhang
Dan-feng Wang
Lin-fang Huang
Qian-wen Lv
Bin Liu
Zhenbin Li
Wei Wei
Hongbin Li
Xiangping Liao
Hui Liu
Xiumei Liu
Hongtao Jin
Junxiang Wang
Yun-yun Fei
Qing-jun Wu
Wen Zhang
Qun Shi
Wen-jie Zheng
Feng-chun Zhang
Fu-lin Tang
Peter E. Lipsky
Xuan Zhang
机构：
[1] Peking Union Medical College Hospital,Department of Rheumatology and Clinical Immunology
[2] Clinical Immunology Center,Department of Radiology
[3] Chinese Academy of Medical Sciences and Peking Union Medical College,Formerly National Institute of Arthritis and Musculoskeletal and Skin Diseases
[4] The Ministry of Education Key Laboratory,Department of Rheumatology
[5] Peking Union Medical College Hospital,Department of Rheumatology
[6] Chinese Academy of Medical Sciences and Peking Union Medical College,Department of Rheumatology
[7] National Institutes of Health,Department of Rheumatology
[8] The Affiliated Hospital of QingDao University Medical College,Department of Nephrology and Rheumatology
[9] The Bethune International Heping Hospital of Hebei,Department of Rheumatology
[10] General Hospital of Tianjin Medical University,Department of Rheumatology
[11] Affiliated Hospital of Inner Mongolia Medical College,Department of Rheumatology
[12] The First People’s Hospital of ChenZhou,Department of Rheumatology
[13] Beijing Dongfang Hospital,The Body Sculpture and Liposuction Center of Plastic Surgery Hospital, Peking Union Medical College
[14] First Hospital of Shanxi Medical University,undefined
[15] Second Hospital of Hebei Medical University,undefined
[16] Third Hospital of Hebei Medical University,undefined
[17] Chinese Academy of Medical Sciences,undefined
[18] AMPEL BioSolutions,undefined
来源：
Arthritis Research & Therapy | / 20卷
关键词：
Rheumatoid arthritis; Hook F; Radiological progression;
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  • [1] Scott DL(2010)Rheumatoid arthritis Lancet (London, England) 376 1094-1108
  • [2] Wolfe F(2013)Therapies for active rheumatoid arthritis after methotrexate failure N Engl J Med. 369 307-318
  • [3] Huizinga TWJ(2009)Treatment of very early rheumatoid arthritis with symptomatic therapy, disease-modifying antirheumatic drugs, or biologic agents: a cost-effectiveness analysis Ann Intern Med. 151 612-621
  • [4] O’Dell JR(2012)Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents Clin Exp Pharmacol Physiol. 39 311-320
  • [5] Mikuls TR(2000)The Chinese anti-inflammatory and immunosuppressive herbal remedy Tripterygium wilfordii Hook F Rheum Dis Clin N Am 26 29-50
  • [6] Taylor TH(2007)Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii Phytochemistry. 68 1172-1178
  • [7] Ahluwalia V(2007)Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae) Phytochemistry. 68 732-766
  • [8] Brophy M(2004)Triptolide, an active component of the Chinese herbal remedy Tripterygium wilfordii Hook F, inhibits production of nitric oxide by decreasing inducible nitric oxide synthase gene transcription Arthritis Rheum. 50 2303-2995
  • [9] Warren SR(1999)Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation J Biol Chem. 274 13443-13450
  • [10] Finckh A(2010)The safety and effectiveness of a chloroform/methanol extract of Tripterygium wilfordii Hook F (T2) plus methotrexate in treating rheumatoid arthritis J Clin Rheumatol. 16 375-378
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