Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation

被引：0
作者：
Marnie E Gelbart
Erica Larschan
Shouyong Peng
Peter J Park
Mitzi I Kuroda
机构：
[1] Brigham & Women's Hospital,Division of Genetics, Department of Medicine
[2] Harvard Medical School,Department of Genetics
[3] Children's Hospital Informatics Program,undefined
[4] Children's Hospital,undefined
来源：
Nature Structural & Molecular Biology | 2009年 / 16卷
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摘要：
Male Drosophila X chromosomes are highly transcribed to achieve dosage parity with females. This process is mediated by the MSL complex, though binding has been detected at only a subset of X chromosomal loci. MSL-dependent histone H4K16 acetylation is now found across the male X, suggesting widespread, but transient, MSL function.
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页码：825 / 832
页数：7
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