Synthesis, spectroscopic characterization and antibacterial activity of lanthanide–tetracycline complexes

被引:0
作者
Gopalakrishnan Karthikeyan
Kuttappan Mohanraj
Kuppanagounder P. Elango
Krishnapillai Girishkumar
机构
[1] Gandhigram Rural Institute (Deemed University),Department of Chemistry
[2] Cochin University of Science and Technology,Department of Applied Chemistry
来源
Transition Metal Chemistry | 2004年 / 29卷
关键词
Escherichia Coli; Antibacterial Activity; Tetracycline; Thermogravimetric Analysis; Staphylococcus Aureus;
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摘要
A series of LnIII–tetracycline complexes of the type [Ln(TC)Cl3]·2H2O [Ln = lanthanum, praseodymium, neodymium, samarium, gadolinium, terbium, dysprosium and yttrium; TC = tetracycline] have been synthesized and characterized by analytical, i.r., electronic, 1H-n.m.r. spectral studies, X-ray diffraction and thermogravimetric analysis. A pentagonal bipyramidal structure has been tentatively proposed for the new complexes. The ligand and the new complexes were tested in vitro to evaluate their activity against the bacteria Escherichia coli and Staphylococcus aureus.
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页码:86 / 90
页数:4
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