Local defects in the nanostructure of the membrane of erythrocytes upon ionizing radiation of blood

被引：4

作者：

Kozlova E.K. ^{[1
,2
]}

Sergunova V.A. ^{[1
]}

Krasavin E.A. ^{[3
]}

Boreyko A.V. ^{[3
]}

Zavialova A.V. ^{[1
]}

Kozlov A.P. ^{[2
]}

Chernysh A.M. ^{[1
,2
]}

机构：

[1] Negovsky Scientific Research Institute of General Reanimatology, Moscow

[2] Sechenov First Moscow State Medical University, Moscow

[3] Joint Institute for Nuclear Research, Dubna

来源：

Physics of Particles and Nuclei Letters | 2016年 / 13卷 / 1期

关键词：

Erythrocyte Membrane; Local Defect; Nucleus Letter; Topological Defect; Erythrocyte Suspension;

D O I：

10.1134/S1547477116010131

中图分类号：

学科分类号：

摘要：

The purpose of the study is to investigate local topological defects in the erythrocyte membranes resulting from the ultraviolet (UV) radiation of blood in vitro. Biological effects in the erythrocytes after exposure to UV radiation at a wavelength of 254 nm are equivalent to those after γ radiation. It has been shown that oxidative processes developing in a suspension upon UV radiation result in the disruption of the nanostructure of the membranes of erythrocytes. In the experiments, typical topological defects in the membrane nanostructure were observed. The parameters of the defects differed from the characteristics of the nanostructure of the control cell membrane without irradiation. The characteristic dimensions of the topological defects are commensurate with the size of the spectrin matrix. As a result of the exposure to the UV radiation, polymorphism of the erythrocytes was observed. © 2016, Pleiades Publishing, Ltd.

引用

页码：140 / 148

页数：8

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