Research in Latin America: opportunities and challenges

[1] Moses H(2015)The anatomy of medical research: US and international comparisons JAMA 313 174-189

[2] Matheson DH(1998)Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome N Engl J Med 338 347-354

[3] Cairns-Smith S(1992)Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients Lancet 339 195-199

[4] Amato MB(2002)Incidence, clinical course, and outcome in 217 patients with acute respiratory distress syndrome Crit Care Med 30 2450-2456

[5] Barbas CS(2013)Differences in sepsis treatment and outcomes between public and private hospitals in Brazil: a multicenter observational study PLoS One 8 e64790-1831

[6] Medeiros DM(2008)Incidence and clinical effects of intra-abdominal hypertension in critically ill patients Crit Care Med 36 1823-2160

[7] Magaldi RB(2015)Organizational characteristics, outcomes, and resource use in 78 Brazilian intensive care units: the ORCHESTRA study Intensive Care Med 41 2149-1443

[8] Schettino GP(2009)Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study Crit Care 13 R92-805

[9] Lorenzi-Filho G(2013)Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover study Intensive Care Med 39 1435-R65

[10] Kairalla RA(2015)Combination of arterial lactate levels and venous-arterial CO Intensive Care Med 41 796-76

[1] Moses H(2015)The anatomy of medical research: US and international comparisons JAMA 313 174-189

[2] Matheson DH(1998)Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome N Engl J Med 338 347-354

[3] Cairns-Smith S(1992)Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients Lancet 339 195-199

[4] Amato MB(2002)Incidence, clinical course, and outcome in 217 patients with acute respiratory distress syndrome Crit Care Med 30 2450-2456

[5] Barbas CS(2013)Differences in sepsis treatment and outcomes between public and private hospitals in Brazil: a multicenter observational study PLoS One 8 e64790-1831

[6] Medeiros DM(2008)Incidence and clinical effects of intra-abdominal hypertension in critically ill patients Crit Care Med 36 1823-2160

[7] Magaldi RB(2015)Organizational characteristics, outcomes, and resource use in 78 Brazilian intensive care units: the ORCHESTRA study Intensive Care Med 41 2149-1443

[8] Schettino GP(2009)Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study Crit Care 13 R92-805

[9] Lorenzi-Filho G(2013)Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover study Intensive Care Med 39 1435-R65

[10] Kairalla RA(2015)Combination of arterial lactate levels and venous-arterial CO Intensive Care Med 41 796-76